Results 61 to 70 of about 231,384 (259)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Influence of composite fibers on the properties of heavy concrete
MATEC Web of Conferences, 2016 The article presents the results of research an effect of glass-plastic fiber on the properties of heavy concrete. It determined that adding glass-plastic fibers in heavy concrete compositions in an amount of 0.5 to 2.5 % by volume leads to decreasing of
Nurtdinov Marsel +2 more
doaj +1 more source
Strength development in adolescents in physical education classes
International Physical Medicine & Rehabilitation Journal, 2019 Objective:The objective of this study was to gain muscle strength in all its variables in adolescents after a strength training program in physical education classes for a period of 12 weeks - a strength training program in physical education classes at a State School of Ponta Pora (Brazil) was applied.
Raphael Oliveira Ramos Franco Netto +2 more
openaire +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
BioResourcesThe primary aim of this work was to determine the effects of production parameters, such as wood species and timber strength classes, on some mechanical properties of cross-laminated timber (CLT) panels using artificial neural network (ANN) prediction ...
Engin Derya Gezer +5 more
doaj +2 more sources
Peculiarities of Use of Dancing Exercises in Physical Education of Female High Schoolers
Physical Education Theory and Methodology, 2015 The purpose of the research is to ground and develop the methods of the use of dancing exercises at physical training classes in high school and to experimentally verify their effectiveness. Research methods.
Т. М. Кравчук +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Strength-Endurance Training Classes [PDF]
Mayo Clinic Proceedings, 2020 Jonathon W. Senefeld, Michael J. Joyner
openaire +1 more source