Results 51 to 60 of about 13,711 (247)
Performance of high strength structural bolts in tension: effects of tolerance classes [PDF]
, 2015 Structural bolts have been manufactured for building construction for hundreds of years. In practice, failure of high strength structural bolts might be caused by their tolerance classes or coating procedures, which may weaken their internal or external ...
Nie, Shi D. +7 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Maderas: Ciencia y Tecnología, 2007 En las últimas décadas en Europa se ha promovido la promulgación de Códigos de Práctica, Directivas y Normas Armonizadas de obligado cumplimiento para los países miembros, que afectan a la madera en la construcción y que son imprescindibles para ...
E Hermoso +2 more
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Science of Gymnastics Journal, 2023 The aim of the research was to examine the effects of isokinetic training on knee stabilizer strength, and whether this increases the efficiency of performing basic gymnastics vaults.
Adis Tabaković +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
In-Class Practice Suggestions for Discovering Students' Strengths/Character Strengths
Humanistic Perspective, 2021 Pozitif psikolojinin önemli çalışma konularından birisi bireyin güçlü yönleridir. Bu çalışmada, güçlü yönlerin/karakter güçlerinin sınıfta keşfedilmesi ve işlevsel olarak kullanılması üzerinde durulmaktadır. Öncelikle, güçlü yönlerin önemi vurgulanmaktadır.
DEMİR, Ramazan, MURAT, Mehmet
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
ON THE FORMULATION OF A TENSORIAL LAMINATE-LEVEL FAILURE CRITERION THROUGH INVARIANTS [PDF]
, 2017 Anisotropic materials, such as fibre-reinforced composite materials, are extensively used in many industrial fields thanks to their mechanical performances.
CATAPANO MONTEMURRO, Anita +2 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source