Results 51 to 60 of about 231,384 (259)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Means of Speed-Strength Abilities Development in Physical Training Classes with 10th Graders
Physical Education Theory and Methodology, 2016 The purpose of the research is to determine the means of development of speed-strength abilities manifesting in jump-offs in jumping exercises in classes with the 10th graders in order to improve the compliance with the standards of physical preparedness.
С. А. Пашкевич +1 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Applied SciencesThe objective of this paper is to evaluate the capability of various steel rope manufacturers to maintain the desired variability within the strength class of wires used in the production of steel ropes.
Marcela Malindzakova, Pavel Peterka
doaj +1 more source
Development of speed and strength abilities of students in mini-football sectional classes
Вестник Северо-Кавказского федерального университетаIntroduction. Modern educational paradigm involves a sociocultural environment creation where there is a citizen’s formation as a subject of spiritual and intellectual self-development with ideology, values, and norms for the reality transformation.
N. L. Nizhneva-Ksenofontova +2 more
doaj +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Study of brazilian structural concrete block conformity
Revista IBRACON de Estruturas e Materiais, 2018 This paper presents a study of the conformity of structural concrete blocks manufactured and used in masonry construction in Brazil. It is based on compressive strength tests, on dimensional analysis and absorption tests of over six thousand samples from
W. C. SANTIAGO, A. T. BECK
doaj +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source