ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Comparison and analysis for prediction accuracy of true triaxial rock strength criterion
To verify the predictive accuracy of existing strength criteria on true triaxial strength experimental data, understand the characteristics of different strength criteria, and provide a basis for selecting strength criteria for engineering applications ...
Shiwei He +4 more
doaj +1 more source
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Surface crack analysis applied to impact damage in a thick graphite-epoxy composite [PDF]
The residual tensile strength of a thick graphite/epoxy composite with impact damage was predicted using surface crack analysis. The damage was localized to a region directly beneath the impact site and extended only part way through the laminate.
Harris, C. E. +2 more
core +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Innovative Data-Driven Machine Learning Approaches for Predicting Sandstone True Triaxial Strength
Given the critical role of true triaxial strength assessment in underground rock and soil engineering design and construction, this study explores sandstone true triaxial strength using data-driven machine learning approaches. Fourteen distinct sandstone
Rui Zhang, Jian Zhou, Zhenyu Wang
doaj +1 more source
The mechanical behavior of cross-rolled beryllium sheet [PDF]
In response to the failure of a conical section of the Insat C satellite during certification testing, the use of beryllium for payload structures, particularly in sheet product form, is being reevaluated.
Castner, W. L. +2 more
core +1 more source
Nanowires: diameter-dependent strength criterion
V Kafka, D Vokoun
openaire +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source

