Results 121 to 130 of about 1,104,488 (305)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Strength of artificially frozen sand with low confining pressure under a three-dimensional stress path

Scientific Reports
True triaxial tests were conducted on artificially frozen sand. The effects of the intermediate principal stress coefficient, temperature and confining pressure on the strength of frozen sand were studied. The stress–strain curves under different initial
Zhaoming Yao, Xinjie Xu, Shuang Liu
doaj   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Diffusion bonding of IN 718 to VM 350 grade maraging steel [PDF]

, 1972
Diffusion bonding studies have been conducted on IN 718, VM 350 and the dissimilar alloy couple, IN 718 to maraging steel. The experimental processing parameters critical to obtaining consistently good diffusion bonds between IN 718 and VM 350 were ...
Biederman, R. R., Crosby, S. R., Reynolds, C. C.   +2 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Cement-stabilized Modified High Fines Melaka Series for Roadbases [PDF]

, 1995
Roads are a crucial infrastructural element in the progress of a nation. Unavailability of suitable base materials causes total building cost to escalate.
Abdul Aziz, Azlan, Maail, Shukri, Megat Mohd Noor, Megat Johari   +2 more
core  

Thermal Phase Mixing During First Order Phase Transitions

, 1994
The dynamics of first order phase transitions are studied in the context of (3+1)-dimensional scalar field theories. Particular attention is paid to the question of quantifying the strength of the transition, and how `weak' and `strong' transitions have ...
A. D. Linde, A. D. Linde, A. D. Linde, A. Dolgov, A. G. Cohen, A. G. Cohen, B. L. Hu, B. Liu, C. Callan, C. Itzykson, D. E. Brahm, D. Lee, E. W. Kolb, F. Abe, F. Abe, G. Gelmini, G. R. Farrar, G. R. Farrar, G. R. Farrar, H. Zink, J. D. Gunton, J. Langer, J. Langer, J. S. Langer, J. S. Langer, J. W. Cahn, Julian Borrill, L. Montanet, M. Alford, M. B. Gavela, M. B. Voloshin, M. Gleiser, M. Gleiser, M. Gleiser, M. Gleiser, M. Gleiser, M. Gleiser, Marcelo Gleiser, P. Arnold, P. Arnold, P. Huet, R. Becker, S. Aluru, S. Coleman, T. W. Stinson, W. Buchmüller   +45 more
core   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source