Results 101 to 110 of about 1,104,488 (305)

Evaluation method for safety of concrete slab stress based on multi-axial strength criterion

open access: yesYantu gongcheng xuebao
The concrete-faced rockfill dams (CFRDs) rely on the key impermeable structures, such as concrete slabs, for their safe operation. Ensuring the safety of the concrete slabs is of the utmost importance.
WANG Fang 1, LI Guoying 1, MI Zhankuan 1, FENG Yelin 2, HUANG Qingfu 2
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Biaxial Constitutive Relation and Strength Criterion of Envelope Materials for Stratospheric Airships

open access: yesAerospace
The performance upgrading of stratospheric airships hinges on breakthroughs in the mechanical properties of envelope materials. As a multi-layer composite, the envelope’s load-bearing layer exhibits orthotropic and nonlinear mechanical behaviors owing to
Zhanbo Li, Yanchu Yang, Rong Cai, Tao Li
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Flux Lattice Melting and the onset of H_c2 fluctuations

open access: yes, 1999
The flux lattice melting temperature in optimally doped YBCO has been shown to be very close to that of the onset of fluctuations around H_{c2}(T). Here, we present a theoretical argument in support of the idea that this occurs because the increased ...
Pierson, Stephen W., Valls, Oriol T.
core   +3 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Criteria for software modularization [PDF]

open access: yes
A central issue in programming practice involves determining the appropriate size and information content of a software module. This study attempted to determine the effectiveness of two widely used criteria for software modularization, strength and size,
Card, David N.   +2 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Evaluation of Flexible Road Pavement Construction State Using Objective Strength Criteria

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2007
This article illustrates that by means of our methodology for evaluation of state of flexible road pavement construction (RPC) it is possible with an adequate precision for practical purposes to measure the remaining resource of pavement construction ...
Saulius Butkevicius   +3 more
doaj  

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