Results 101 to 110 of about 261,552 (302)

Strength criterion of rock mass considering the damage and effect of joint dip angle. [PDF]

Sci Rep, 2022
Li Y, Zhang H, Chen M, Meng X, Shen Y, Liu H, Lu Y.   +6 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Evaluation of Flexible Road Pavement Construction State Using Objective Strength Criteria

The Baltic Journal of Road and Bridge Engineering, 2007
This article illustrates that by means of our methodology for evaluation of state of flexible road pavement construction (RPC) it is possible with an adequate precision for practical purposes to measure the remaining resource of pavement construction ...
Saulius Butkevicius, Kazys Petkevicius, Kazys Petkevicius, Ipolitas Zenonas Kamaitis   +3 more
doaj  

Biaxial Constitutive Relation and Strength Criterion of Envelope Materials for Stratospheric Airships

Aerospace
The performance upgrading of stratospheric airships hinges on breakthroughs in the mechanical properties of envelope materials. As a multi-layer composite, the envelope’s load-bearing layer exhibits orthotropic and nonlinear mechanical behaviors owing to
Zhanbo Li, Yanchu Yang, Rong Cai, Tao Li
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Influence of Rock Properties in Estimating Rock Strength for Shallow Underground Structures in Weak Rocks

Indonesian Journal on Geoscience, 2018
DOI: 10.17014/ijog.5.2.93-105Two popular rock strength criteria, the linear Coulomb and non-linear Hoek-Brown, are widely used in underground designs. These two criteria may be applied differently depending on rock conditions.
Didi Supriadi Agustawijaya
doaj   +1 more source

History-sensitive accumulation rules for life-time prediction under variable loading

, 2011
This is the post-print version of the article. The official published version can be obtained from the link below - Copyright @ 2011 SpringerA general form of temporal strength conditions under variable creep loading is employed to formulate several new ...
Mikhailov, SE, S. E. Mikhailov, I. V. Namestnikova, Namestnikova, IV   +3 more
core   +1 more source

Gross plastic deformation of axisymmetric pressure vessel heads [PDF]

, 2006
The gross plastic deformation and associated plastic loads of four axisymmetric torispherical pressure vessels are determined by two criteria of plastic collapse: the ASME twice elastic slope (TES) criterion and the recently proposed plastic work ...
Camilleri, D., Camilleri, Duncan, Hamilton, Robert, Mackenzie, Donald, Mackenzie, D., Hamilton, R.   +5 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source