Results 91 to 100 of about 261,552 (302)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

A Performance Dependent Failure Criterion for Normal & High Strength Concretes

open access: yes, 2009
A new approach to describe the maximum strength criterion of concretes with different strength capacities is formulated. The proposed failure criterion incorporates the so-called “performance parameter” (βP) that controls the dependence of the maximum ...
Etse, Jose Guillermo   +2 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Evaluation method for safety of concrete slab stress based on multi-axial strength criterion

open access: yesYantu gongcheng xuebao
The concrete-faced rockfill dams (CFRDs) rely on the key impermeable structures, such as concrete slabs, for their safe operation. Ensuring the safety of the concrete slabs is of the utmost importance.
WANG Fang 1, LI Guoying 1, MI Zhankuan 1, FENG Yelin 2, HUANG Qingfu 2
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

The Maastricht Inflation Criterion: "Saints" and "Sinners" [PDF]

open access: yes
The Maastricht inflation criterion, designed in the early 1990s to bring “high-inflation†EU countries into line with “low-inflation†countries prior to the introduction of the euro, poses challenges for both new EU member countries and the ...
Ales Bulir, Jaromir Hurnik
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Strength of textile Composites

open access: yes, 2006
For the prediction of composite strengths with representative volume elements (RVE) a thorough understanding of the ongoing failure mechanisms is needed. This again is influenced by the manufacturing process.
Ernst, Gerald   +2 more
core  

Failure criterion for metallic glasses

open access: yes, 2011
Metallic glasses exhibit not only multiple failure modes but also differences in ultimate strength, plastic strain to fracture and asymmetric deviation of failure angles from 45 degrees between tension and compression.
Dai, LH (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China   +4 more
core   +1 more source

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