Results 71 to 80 of about 261,552 (302)

Strength criterion of composite solid propellants under dynamic loading

open access: yes, 2018
Based on the dynamic loading (1-100 s−1) experiments under different temperatures (223–298 K) and stress states, uniaxial and biaxial strength criterion of a Hydroxyl-terminated polybutadiene (HTPB) based composite solid propellant were further ...
Zhe-jun Wang   +3 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

A comparative analysis of several nonlocal fracture criteria

open access: yes, 1998
Comparative analysis has been carried out for three nonlocal fracture criteria (NLFC) in application to plane problems: the average stress fracture criterion (ASFC), the minimum stress fracture criterion (MSFC) and the fictitious crack fracture criterion
Mikhailov, SE, Isupov, LP
core  

A probabilistic model for the high cycle fatigue behaviour of cast aluminium alloys subject to complex loads [PDF]

open access: yes, 2013
Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0142112312002472This article is dedicated to the high cycle fatigue behaviour of cast hypo-eutectic Al–Si alloys and in particular the AlSi7Cu05Mg03 alloy.
PESSARD, Etienne   +3 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Experimental studies of scale effects on shear strength, and deformation of rock joints [PDF]

open access: yes, 1980
The effect of scale on shear strength is studied by performing direct shear tests on different sized samples of large joints. A rubber moulding system is used to obtain impressions of the roughness from a variety of natural joint surfaces.
Bandis, Stavros
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

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