Results 31 to 40 of about 2,682,010 (187)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Estimation of strength degradation under elevated temperature and humidity for engineering plastic
Nihon Kikai Gakkai ronbunshu, 2019 A large quantity of engineering plastics are used in electric industrial products. It is necessary to estimate the life of the product made of engineering plastics because of its shorter life and lower strength than some of ceramics or metals ...
Yuko SAWADA, Daisuke ECHIZENYA
doaj +1 more source
A consecutive joint shear strength model considering the 3D roughness of real contact joint surface
International Journal of Mining Science and Technology, 2023 A consecutive joint shear strength model for soft rock joints is proposed in this paper, which takes into account the degradation law of the actual contact three-dimensional (3D) roughness.
Liren Ban +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Meitan kexue jishuFreeze-thaw damage to rock masses on slopes constitutes a major hazard in open-pit mining operations, particularly in the cold regions of the western area.
Haotian XIE +5 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
STRENGTH-CYCLE CURVES FOR MULTI-AXIAL FATIGUE OF POLYESTER REINFORCED BY GLASS FIBER
Journal of Engineering and Sustainable Development, 2016 This study discusses the development of a multi-axial fatigue testing machine, and studies the fatigue behavior of cantilever glass fiber composites beam under in phase bending-torsion dynamic loadings.
Samira Kareem Radhi +2 more
doaj
Shuiwen dizhi gongcheng dizhiCurrent methods for calculating the seismic stability of planar sliding rock slopes inadequately account for the effect of structural plane roughness and tend to overestimate the influence of vibration wear and relative movement velocity on strength ...
Hongyan LIU +6 more
doaj +1 more source
Effects of type I collagen degradation on the durability of three adhesive systems in the early phase of dentin bonding. [PDF]
PLoS ONE, 2015 OBJECTIVE:This study was designed to evaluate the effects of type I collagen degradation on the durability of three adhesive systems in the early phase of dentin bonding.
Lin Hu +6 more
doaj +1 more source
Case Studies in Construction Materials, 2021 Limited information is known about the effects of bond strength degradation during installation on the bond's quality and performance between fiber-reinforced polymer (FRP) reinforcement and substrate material.
Rajai Z. Al-Rousan, Ayah Alkhawaldeh
doaj +1 more source