Results 51 to 60 of about 2,115,496 (315)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Blended cement hydration assessment by thermogravimetric analysis and isothermal calorimetry

MATEC Web of Conferences, 2018
In the present study, the hydration of Portland cement pastes containing 5%, 10%, 15% and 20% tuff, limestone filler and granodiorite was investigated by thermogravimetric analysis coupled with differential scanning calorimetry and microcalorimetry ...
Meziani Meriem, Chelouah Nasser, Amiri Ouali, Leklou Nordine   +3 more
doaj   +2 more sources

The effect of temperature on strength differential and material effort of steam turbine rotors [PDF]

AIP Conference Proceedings, 2020
The paper presents the results of mechanical tensile and compression tests performed at a range of temperatures on specimens made from 2%CrMoV steel. Variation of strength differential coefficent was found and considered in numerical analyses of material effort of a steam turbine rotor subject to thermomechanical loading.
Waldemar Dudda, Mariusz Banaszkiewicz, Janusz Badur   +2 more
openaire   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Limit Condition for Anisotropic Materials with Asymmetric Elastic Range

Engineering Transactions, 2014
In the paper a new proposition of an energy-based hypothesis of material effort is intro- duced. It is based on the concept of influence functions introduced by Burzyński [3] and on the concept of decomposition of elastic energy density introduced by ...
Janina OSTROWSKA–MACIEJEWSKA, Ryszard Bolesław PĘCHERSKI, Paweł SZEPTYŃSKI   +2 more
doaj   +1 more source

Development of Halloysite Loaded Polypropylene Sutures with Enhanced Mechanical and Thermal Properties

Cumhuriyet Science Journal, 2023
Polypropylene is a crucial polymeric material in modern life, especially in the packaging and food industry, as well as the biomedical field. This study aimed to enhance the mechanical properties of polypropylene structures used as surgical suture ...
Fadime Nülüfer Kıvılcım
doaj   +1 more source

Impact of Acquisitions on CEO pay [PDF]

, 2012
I examine the impact of acquisition on the pay of CEOs of S&P 1500 firms from 1994-2010. I find insignificant effect of firm performance on post-acquisition CEO pay. Controlling for firm size, CEOs are paid a premium in post-acquisition pay.
Homroy, Swarnodeep
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Study on the Impact of Combined Action of Temperature Differential and Freeze–Thaw Cycle on the Durability of Cement Concrete

Buildings
As a primary construction material, concrete plays a vital role in the development of infrastructure, including bridges, highways, and large-scale buildings.
Chengyun Tao, Lin Dong, Mingyang Suo
doaj   +1 more source

Thermal Radiation, Chemical Reaction, Viscous and Joule Dissipation Effects on MHD Flow Embedded in a Porous Medium

International Journal of Applied Mechanics and Engineering, 2019
An analysis is presented to study the effects of thermal radiation, chemical reaction, viscous and Joule dissipation on MHD free convection flow between a pair of infinite vertical Couette channel walls embedded in a porous medium.
B. Zigta
doaj   +1 more source