Results 81 to 90 of about 9,698,512 (350)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Effect of Sports and Growth on Hamstrings and Quadriceps Development in Young Female Athletes: Cross-Sectional Study

Sports, 2019
Context: Lower extremity muscular strength may vary by different sport participation during growth process. Objective: To investigate effect of sport participation and growth by comparing strength of the hamstrings, quadriceps, and hamstrings to ...
Dai Sugimoto, Dennis R. Borg, Anna N. Brilliant, William P. Meehan, Lyle J. Micheli, Ellen T. Geminiani   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Comparing the Isometric Strength of the Shoulder and Scapulothoracic Muscles in Volleyball and Futsal Athletes

Physical Treatments, 2017
Purpose: This study aimed to evaluate the symmetry of the isometric strength of the shoulder and scapulothoracic muscles in volleyball and futsal athletes.
Afshin Rasouli, Aliashraf Jamshidi, Soheil Sohani   +2 more
doaj  

Proposal of a novel APPLE-KNOT undulator by selecting the KNOT field as the dominant magnetic field

Journal of Synchrotron Radiation
The APPLE-KNOT undulator forms composite magnetic fields by superimposing an APPLE field and a KNOT field with different period lengths, in which one serves as the dominant field to approach the target photon energy and the other acts as an additional ...
Binghao Zhang, Chao Chen, Yuanfang Xu, Zhouyu Zhao, Heting Li   +4 more
doaj   +1 more source

Strength Properties of Grout for Strata Reinforcement [PDF]

, 2017
An experimental study was carried out on grout samples prepared from both Stratabinder and BU100 cementitious products. Samples were prepared with various water to grout ratios and tested for uniaxial compressive and shear strength.
Aziz, Naj, Majoor, Dean, Dean Majoor, Ali Mirzaghorbanali, Mirzaghorbanali, Ali, Naj Aziz   +5 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Numerical Analysis for the Progressive Failure of Binary-Medium Interface under Shearing

Advances in Civil Engineering, 2018
Binary-medium specimens were fabricated using the particle flow code, and the shear strength, dilatancy, and failure behavior of the binary-medium specimens with different bond strength ratios (0.25, 0.5, 0.75, and 1.0) under different normal stresses ...
Rihong Cao, Wenyu Tang, Hang Lin, Xiang Fan   +3 more
doaj   +1 more source

Light Intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study [PDF]

, 2015
Identifying modifiable determinants of fat mass and muscle strength in older adults is important given their impact on physical functioning and health.
Cooper, R, Glynn, Nancy W, Todd Manini, Nancy W Glynn, Rachel Cooper, Marco Pahor, Group, LIFE Study, Walter T Ambrosius, Fielding, R, King, AC, Ambrosius, Walter T, David Bann, Pahor, M, David Bann (688911), Abby C. King (407214), Todd Manini (688913), Mary M. McDermott (688915), Nancy W. Glynn (688916), Timothy Church, Bann, David, Glynn, NW, Bann, D, Gill, T, Gill, Thomas, Cooper, Rachel, Roger Fielding, LIFE Study Group, Walter T. Ambrosius (579783), Anda Botoseneanu, Don Hire, King, Abby C, Thomas M Gill, Botoseneanu, A, Thomas Gill (688918), Pahor, Marco, McDermott, MM, McDermott, Mary M, Gill, TM, Hire, D, Manini, Todd, Don Hire (688912), Ambrosius, WT, Mary M McDermott, Botoseneanu, Anda, Anda Botoseneanu (688914), Hire, Don, Abby C King, Fielding, Roger, Church, Timothy, , LIFE Study Group, Manini, T, Roger Fielding (688917), Timothy Church (501433), Marco Pahor (331192), Church, T, Rachel Cooper (188902)   +55 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source