Results 91 to 100 of about 3,528,209 (331)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Pseudo-Static Experiment and Analysis on Seismic Behavior of the RC Columns Strengthened by GHPFRCC

open access: yesPolish Maritime Research, 2015
Green high performance fiber reinforced cementitious composites (GHPFRCC) are a new class of sustainable cementitious composites, employing a high volume of fly ash to replace cement.
Li Xiuling, Wang Juan, Luo Min
doaj   +1 more source

Strategies to Strengthen Youth Leadership and Youth Participation Opportunities in Central Appalachia [PDF]

open access: yes, 2015
The purpose of this study was to assess opportunities for strengthening youth leadership and participation in the Central Appalachian region. In particular, authors Rebecca O’Doherty, Ada Smith, Ben Spangler, Elandria Williams, and Katie Richards ...
O\u27Doherty, Rebecca   +4 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Strengthening healthcare through family medicine training in The Gambia: The journey so far

open access: yesAfrican Journal of Primary Health Care & Family Medicine
According to the World Health Organizations (WHO) family medicine forms the bedrock upon for accessible, affordable and equitable healthcare for any country. The need for family doctors is more acute for low income countries like The Gambia. More so that
Abraham N. Gyuse   +4 more
doaj   +1 more source

Reducing soil degradation to increase resilience to climate change and strengthen livelihoods in Ethiopia. [PDF]

open access: yes, 2019
Soil degradation is a major problem in Ethiopia. Depletion of soil organic matter is a cause of low agricultural productivity, as soils become less fertile and less resilient to extreme weather events, which are expected to increase with climate change ...
International Water Management Institute
core  

New data strengthen the connection between Short Range Correlations and the EMC effect

open access: yes, 2012
Recently published measurements of the two nucleon short range correlation ($NN$-SRC) scaling factors, $a_2(A/d)$, strengthen the previously observed correlation between the magnitude of the EMC effect measured in electron deep inelastic scattering at $0.
Hen, O., Piasetzky, E., Weinstein, L. B.
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

BEHAVIOR OF REINFORCED CONCRETE CONTINUOUS DEEP BEAMS WITH OPENINGS AND USING MULTIPLE TYPES OF STRENGTHING

open access: yesMağallaẗ Al-kūfaẗ Al-handasiyyaẗ
In this research, thirteen specimens of reinforced concrete continuous deep beams were cast and tested. One was the main reference without openings, three were a reference for each style depending on the arrangement of the openings, while the other nine ...
Huda Basim kitab, Muhammad Abed Attiya
doaj   +1 more source

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