Results 81 to 90 of about 2,442,222 (305)
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
BEHAVIOR OF HYBRID REINFORCED CONCRETE DEEP BEAMS WITH WEB OPENINGS UNDER REPEATED LOADING
Journal of Engineering and Sustainable Development, 2019 This research aims to study experimentally the behavior of hybrid deep beams when subjected to two point's monotonic and repeated loading in the presence or absence of web openings.
Sawsan Akram Hassan +1 more
doaj
Journal of the International Association of Providers of AIDS Care, 2019 A Community Health System Strengthening model, which mobilizes communities by applying quality improvement, was used in 39 communities around 3 health centers in Gaza Province, Mozambique, to increase identification of pregnant women and support them to ...
Kim Ethier Stover MA +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Journal of Natural FibersModern research is focused on the discovery of new compounds that meet the requirements of modern construction. An example of low energy consumption is that buildings consume between 20% and 40% of energy.
Abdelkader Fidjah +7 more
doaj +1 more source
How to Strengthen and Reform Indian Medical Education System: Is Nationalization the Only Answer? [PDF]
, 2010 As India marches towards an exciting new future of growth and progress, medical education will play pivotal role in crafting a sustained development agenda.
Manjula, CG, Yathish, TR
core +1 more source
Complementarity and Identification
, 2016 This paper examines the identification power of assumptions that formalize the notion of complementarity in the context of a nonparametric bounds analysis of treatment response.
Twinam, Tate
core +1 more source
A Strengthening of Brooks' Theorem
Journal of Combinatorial Theory, Series B, 1999 This paper mainly proves the conjecture due to \textit{A. Beutelspacher} and \textit{P.-R. Hering} [Ars Comb. 18, 201-216 (1984; Zbl 0554.05025)]. More precisely, the author proves that for sufficiently large \(\Delta\), any graph with maximum degree at most \(\Delta\) and no cliques of size \(\Delta\) has a \(\Delta-1\) colouring.
openaire +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source