Results 91 to 100 of about 1,170,552 (248)

Active Ageing Strategies to Strengthen Social Inclusion : discussion paper. [PDF]

In the coming years, the share of elderly people in the whole population will strongly increase in all European Union countries. It is therefore necessary to implement a social inclusion strategy targeted towards older people both for economic and social
Sterdyniak, Henri
core  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Computing best medium to strengthen communities [PDF]

, 2013
KUCHING: In the present globalisation era, computing is the best medium to strengthen our communities with the latest information and ...
New Sarawak, Tribune, New Sarawak Trinune   +1 more
core   +1 more source

Increasing HIV-Free Survival of Infants: Reorganizing Care Using Quality Improvement for the Optimal Health and Nutrition of HIV-Positive Women and Their Exposed Infants in Uganda

Journal of the International Association of Providers of AIDS Care, 2019
Reorganizing service delivery to integrate nutrition and infant and young child feeding (IYCF) with prevention of mother-to-child transmission (PMTCT) is important for improving outcomes of HIV-positive mothers and HIV-exposed infants (HEIs).
Tamara Nsubuga-Nyombi BSc, MPHDC, Esther Karamagi MBChB, MSc, Linda Nabitaka MBChB, MCH, Samalie Namukose BSc, MSc, Jacqueline Calnan MPH, Sheila Nyakwezi BSc, MSc, Hanifa Bachou PhD, MSc, MBChB, Lazarus Oucul MCCP, Aurora Ose Amoah PhD, MPP, MPH   +8 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Brain health-directed policymaking : A new concept to strengthen democracy

, 2022
Brain health-directed policymaking : A new concept to strengthen ...
Jorge Jraissati (14671889), Walter D Dawson (14671877), Michael Berk (13060851), Agustin Ibanez (129179), Virginia Bennett (14671865), Mark T D'Esposito (14671874), Rym Ayadi (14671862), Harris A Eyre (13377051), William Hynes (13377057), Carol Graham (6704302), Michael Freeman (478072), Ian H Robertson (12601099), Andrew Carlo (14671871), Christine Yu Moutier (14671907), Robert M Bilder (14671868), Jair C Soares (13578073), Erin Smith (271371), Karen Rommelfanger (14671898), Sebastian F Winter (14671904), Ryan Abbott (13303419), Lynne Corner (5951882), James T Hackett (14671883), Chee H Ng (6947630), Antonella Santuccione Chadha (14671901), Eric A Storch (5513288), Wolfgang H Oertel (14671895), Frederic Destrebecq (14671880), David G Angeler (13377048), Zoltan Sarnyai (798744), Shuo Chen (260745), Dilip V Jeste (14671886), Facundo Manes (129204), Michael D Matthews (14671892)   +32 more
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source