Results 141 to 150 of about 2,684,306 (351)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Statistical properties and material partial factors of ECC material based on shear failure member

open access: yesFrontiers in Materials
Engineered Cementitious Composite (ECC) material, as a hybrid material, also has uncertainties. In addition, the shear failure mechanism of reinforced ECC (R-ECC) member is different from that of ordinary reinforced concrete (RC) member, and a new ...
Shixiang Yi   +4 more
doaj   +1 more source

Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies

open access: yesBritish medical journal, 2007
Rothwell   +7 more
semanticscholar   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

THE OPTIMIZATION OF THE MODEL OF THE STRENGTHENED LAYER BY THE SURFACE STRENGTHENING

open access: yesВестник Донского государственного технического университета, 2009
The parameters of the imitative model of multilayer conductive ferromagnetic media to achieve the optimal precision of modeling are determined. The experimental investigation of the distribution of physicomechanical and electromagnetic properties along the thickness of the sample have been carried out.
А.А. LAVRENTYEV   +3 more
openaire   +2 more sources

Encouraging diversity - strengthening cohesion [PDF]

open access: yes, 2006
ENCOURAGING DIVERSITY - STRENGTHENING COHESION Encouraging diversity - strengthening cohesion (Rights reserved) (-

core  

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

Use of zinc sulfate for the development of zinc-fortified meat products from broiler meat

open access: yesJournal of Advanced Veterinary and Animal Research
Objective: The study aimed to assess the feasibility of incorporating food-grade zinc sulfate (ZnSO4) for making zinc-fortified meatballs from broiler meat.
Asma Sultana   +8 more
doaj   +1 more source

A model for precipitation kinetics and hardening in Al-Cu-Mg alloys

open access: yes, 2007
A physically-based numerical model is developed to predict the microstructural evolution and strengthening in Al Cu Mg alloys during isothermal treatments.
I.N. Khan   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy