Results 51 to 60 of about 694,109 (303)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Study on Strengthening Mechanism of Dispersion Strengthened Alloy
Journal of the Japan Society of Powder and Powder Metallurgy, 1972 To account for the strengthening mechanism in the dispersion hardened 13CrMoTi steel, an analysis of the structural change during the heating at the specimens subjected to hot-working after sintering was made by means of X-ray diffraction method. The results obtained are as follows:1) The internal strain is introduced into the matrix of the sintered ...
Takashi Daikoku +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The strengthening mechanism synergy of heat-treated 3D printed Al-Sc alloy
Virtual and Physical Prototyping, 2023 According to the material nature, aluminium alloys are widely applied in aerospace, construction and automotive applications due to their characteristics, such as lightweight, good formability and good corrosion resistance.
Che-Nan Kuo, Po-Chun Peng
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Processes, microstructure and properties of vanadium microalloyed steels [PDF]
, 2009 Vanadium as an important alloying element in steels was initially associated with the properties achieved following tempering. Interest in the microstructure was stimulated by the advent of transmission electron microscopes with a resolution of ~1nm ...
Baker, T.N.
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Microstructure and strength of metals processed by severe plastic deformation [PDF]
, 2006 The microstructure of f.c.c. metals (Al, Cu, Ni) and alloys (Al-Mg) processed by severe plastic deformation (SPD) methods is studied by X-ray diffraction line profile analysis.
Chinh, Nguyen Quang +3 more
core
Boards as an Accountability Mechanism [PDF]
, 2014 Boards are central to the system of nonprofit accountability, but their adequacy has been increasingly questioned by policymakers, media, researchers and others.
Ostrower, Francie Dr.
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source