Results 71 to 80 of about 3,758,516 (308)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A Review on Nano-Scale Precipitation in Steels

Technologies, 2018
Nano-scale precipitation strengthened steels have drawn increasing attention from the materials community recently due to their excellent mechanical behaviors at room temperature, high specific strength to weight ratio, superior radiation resistivity ...
Hao Jie Kong, Chain Tsuan Liu
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Molecular Dynamics Simulation Connections and Mechanical Properties of Cu/Al Explosion Shock Interface

Journal of Aeronautical Materials, 2017
Based on the molecular dynamics (MD) method, transient explosive welding process of Cu/Al junction point was revealed from the microscopic aspect, and mechanical properties and machinability of the Cu/Al nano-weldment were studied.
ZHANG Yan, XIAO Wanshen
doaj   +1 more source

Substructural Strengthening in Molybdenum and Mo-33Re

, 1985
Strengthening from defect substructures has been studied in Mo-33Re deformed in tension and by cold rolling, and in shock-loaded molybdenum and Mo-33Re.
Mikkola, D. E., Wright, R. N., Brusso, J. A.   +2 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Effects of Annealing Temperature and Mo Alloying Element on Microstructures and Mechanical Properties of Fe-18Mn-8Al-1C-3Cu Lightweight Steel

Metals
As a new generation of structural materials, Fe-Mn-Al-C lightweight steels with low density, high strength, and excellent strength-toughness properties have shown significant application potential in fields such as transportation, aerospace, and energy ...
Shibo Wang, Peng Li, Hua Ding
doaj   +1 more source

Seismic strengthening of beam-column joints with multidirectional CFRP laminates [PDF]

, 2012
An experimental program was carried out to analyse the potentialities of a technique based on the use of multidirectional CFRP laminates (MDL-CFRP) for the seismic repair and strengthening of reinforced concrete (RC) beam-column joints. This experimental
Costa, A., Barros, Joaquim A. O., Varum, Humberto, Barros, J., Varum, H., Sena-Cruz, José, Coelho, M., Fernandes, P., Sena-Cruz, J., Melo, José, Costa, Aníbal, Coelho, Mário Rui Freitas, Melo, J., Fernandes, Pedro Miguel Gomes   +13 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source