Results 81 to 90 of about 694,109 (303)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The vacuum horizontal continuous casting method was used for preparing Cu-4.5 wt.% Ag alloy rod containing few oxygen. The evolution of microstructure was observed by metallographic microscope (OM), scanning electron microscope (SEM) and transmission ...
Linsheng Tang +5 more
doaj +1 more source
On broad iron K-alpha lines in Seyfert 1 galaxies
The X-ray spectrum obtained by Tanaka et al from a long observation of the active galaxy MCG$-6-30-15$ shows a broad iron K$\alpha$ line skewed to low energies.
Brandt, W. N. +7 more
core +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Nanoscale α Phase Enables Excellent Strength–Ductility Balance in TC21 Titanium Alloy
The limited ductility of conventional titanium alloys significantly limits their application in critical load-bearing components. To overcome this limitation, a Ti-6Al-2Mo-2Nb-2Zr-2Sn titanium alloy (TC21) was subjected to warm rolling at 500 and 600 °C ...
Keyu Ma +4 more
doaj +1 more source
Strengthening mechanism and thermal deformation behavior of Al-12Si/Fe piston composite
The present paper aims the investigation on the influence of Fe based amorphous on strength of aluminum alloy (Al-12Si), and the thermal deformation behavior of new Al-12Si/Fe base amorphous composites. On this foundation, a heat flow stress model of the
Hao Yang +4 more
doaj +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Synthesis, microstructure, and mechanical properties of in situ TiB2/Al-4.5Cu composites
In situ TiB2/Al-4.5Cu composites with different TiB2 particle amounts were fabricated by the salt-metal reaction technique. The effects of in situ TiB2 on the microstructure and mechanical properties of Al-4.5Cu alloy were studied in this paper.
Li Hongying +3 more
doaj +1 more source
AE44-2 magnesium (Mg) alloys were fabricated by gravity casting (GC), high pressure die casting (HPDC), and high vacuum assisted high pressure die casting (HVHPDC).
Taihe Le +5 more
doaj +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source

