Results 91 to 100 of about 10,399,078 (343)
, 2021 It is the key to the concrete repair and strengthening construction that the base concrete has a certain quality and strength. Based on the strengthening mechanism of sodium silicate, the sodium silicate was modified to develop a kind of compound ...
Xiong Ying +6 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Cailiao gongchengThe medium and high volume fraction SiCp/Al composites were prepared by hot isostatic pressing powder metallurgy process with volume fractions of 35%, 45% and 55% using 2024 and 6061 aluminum alloys as the matrix, respectively. The effect of matrix alloy
CUI Yan +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Research progress in additive manufacturing of AlCoCrFeNi2.1 eutectic high-entropy alloys
Cailiao gongchengAlCoCrFeNi2.1 eutectic high-entropy alloy is characterized by a fine, homogeneous, and regular lamellar structure, as well as good organizational structure and mechanical properties with both strength and plasticity over a wide range of temperature (70 ...
QIU Hefang +5 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Strengthening mechanism and bio-degradability of a silk-based polymer composite
, 2012 Silkworm silk fibre is one kind of well recognized animal fibres for bio-medical engineering and surgical operation applications because of its mechanical, biocompatible and bio-resorbable properties.
Ho, Mei-Po
core
Strengthening Grievance Mechanisms in Georgia
, 2022 This note offers an overview of challenges and lessons learned from the 2019 effort, then reviews each of the PIU’s GMs, including the respective GM complaint uptake channels, overall GM architecture, registration and categorization processes, investigation and resolution mechanisms, related communication efforts, and grievance-related data.
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source