Results 121 to 130 of about 52,789 (213)

Group A streptococcal infections in Alberta, Canada 2018-2023. [PDF]

open access: yesEpidemiol Infect
Tyrrell GJ   +5 more
europepmc   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

open access: yesiMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

Comprehensive spatial profiling reveals transitional microbiome dynamics and microbial heterogeneity in pediatric adenoid hypertrophy

open access: yesiMetaOmics, EarlyView.
This study characterizes the upper respiratory microbiome in 276 children (101 Adenoid hypertrophy (AH) 119 Adenotonsillar hypertrophy (ATH), 11 Tonsil hypertrophy (TH), and 45 healthy controls by analyzing 1149 samples across five distinct niches: nasopharyngeal swabs (NS), adenoid swab (AS), and tonsil swabs (TS), plus adenoid tissues (AT) and tonsil
Kaining Chen   +28 more
wiley   +1 more source

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis

open access: yesiMeta, EarlyView.
Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.
Yi Jin   +21 more
wiley   +1 more source

The role of human microbiota in breast cancer pathogenesis and treatment

open access: yesiMeta, EarlyView.
The human microbiota contributes to breast cancer pathogenesis and treatment response through interactions involving the oral, gut, and breast microbial niches. (Left) Multi‐site dysbiosis is characterized by altered microbial composition and abundance across different anatomical sites.
Jie Qiu   +9 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

A dendrimer enhanced CRISPR/Cas12a performance for the evaluation of acidogenic capacity in cariogenic bacteria

open access: yesInterdisciplinary Medicine, EarlyView.
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang   +4 more
wiley   +1 more source

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