Results 131 to 140 of about 52,789 (213)

Integrating network pharmacology, molecular docking, and molecular dynamics simulations to explore potential compounds and mechanisms of <i>Coptis chinensis</i> in treating streptococcal infections. [PDF]

PeerJ
Qi W, Shi B, Tang W, Zeng J, Zhuo M, Ma H.   +5 more
europepmc   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

Interdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao, Panpan Qiao, Yujing Zeng, Murtaza Sayed, Qin Mi, Juan Zhang, Genxi Li   +6 more
wiley   +1 more source

Role of viral coinfection in post-pandemic invasive Group A streptococcal infections in adults, a nation-wide cohort study (iGASWISS). [PDF]

Eur J Clin Microbiol Infect Dis
Musumeci S, MacPhail A, Weisser Rohacek M, Erba A, Goldenberger D, Lang C, Colin-Benoit E, Leib SL, Sendi P, Chuard C, Erard V, Fournier C, Cobuccio L, Tagini F, Bertelli C, Senn L, Sommerstein R, Blättler G, Vieira Gomes C, Moraz M, Emonet S, Strahm C, Kohler P, Seiffert SN, Herzog K, Vuichard Gysin D, Brugger SD, Nolte O, Egli A, Weller D, Andrianaki AM, Zinkernagel AS, Vu DL, Uribe Caparros A, Laurie G, Gaia N, Lazarevic V, François P, Schrenzel J.   +38 more
europepmc   +1 more source

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam, Pattamaporn Deechart, Nuntaree Chaichanawongsaroj   +2 more
wiley   +1 more source

Risk of Household Secondary Invasive Group A Streptococcal Infections After a Prophylaxis Policy Change.

JAMA Netw Open
de Gier B, Vlaminckx BJM, van Roon A, Knol MJ, Te Wierik MJM, Notermans DW, de Melker HE, van Sorge NM.   +7 more
europepmc   +1 more source

The role of previous streptococcal infections in adult patients with obsessive-compulsive disorder: a research study. [PDF]

CNS Spectr
Marazziti D, Palermo S, Arone A, Carbone MG, Massa L, Crowther LF, Crivelli NSB, Gurrieri R, Weiss F, Mucci F, Dell'Osso L.   +10 more
europepmc   +1 more source

Gut Microbiota: A Reservoir for Extraintestinal Bacterial Infections in Febrile Term Infants

iLABMED, EarlyView.
Ran Wang, Renqiang Yu
wiley   +1 more source

Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative

Journal of Hospital Medicine, EarlyView.
Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski, Karen Howard, Hannah Imlay, Chaorong Wu, Christy L. Hopkins, Valerie M. Vaughn, Emily S. Spivak   +6 more
wiley   +1 more source

Group B streptococcal infections in pregnancy and early life. [PDF]

Clin Microbiol Rev
Manuel G, Twentyman J, Noble K, Eastman AJ, Aronoff DM, Seepersaud R, Rajagopal L, Adams Waldorf KM.   +7 more
europepmc   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source