Results 251 to 260 of about 43,451 (311)

Polypept(o)ide‐Based Core–Shell Bottlebrush Polymers: A Versatile Platform for Drug Encapsulation

open access: yesMacromolecular Bioscience, EarlyView.
This study developed polypept(o)ide‐based core–shell brushes (CSBs) with tunable sizes (Rh: 17–70 nm) for hydrophobic drug delivery. CSBs achieved 10% dasatinib loading through π–π interactions, enabling sustained release over 72 h. Notably, CSB‐dasatinib complexes showed comparable cell viability reduction to the free drug in U‐87 MG cells ...
Bonan Zhao   +6 more
wiley   +1 more source

The Potential of Ruthenium(II) Tris‐Bidentate Complexes as Multifunctional Photo‐Initiators

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study explores the use of an antibacterial ruthenium(II) based photo‐initiator for the photo‐polymerization of gelatin hydrogels. Antibacterial activity is shown to be retained in fabricated hydrogels. The photo‐initiator is utilized in the interstitial fluid of a hybrid granular hydrogel system to generate a proof‐of‐concept injectable system for
Quinn V. C. van Hilst   +14 more
wiley   +1 more source

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

Invasive group A streptococcal infections requiring admission to ICU: a nationwide, multicenter, retrospective study (ISTRE study). [PDF]

open access: yesCrit Care
Orieux A   +86 more
europepmc   +1 more source

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