Results 311 to 320 of about 3,232,787 (374)

Early-onset group B streptococcal infections in five Nordic countries with different prevention policies, 1995 to 2019. [PDF]

Euro Surveill
Björklund V, Saxén H, Hertting O, Malchau Carlsen EL, Hoffmann S, Håkansson S, Stefánsson Thors V, Haraldsson Á, Brigtsen AK, Döllner H, Huhtamäki H, Pokka T, Ruuska TS, Nordic Research Network for Paediatric Infectious Diseases Study Group (NORDPID).   +13 more
europepmc   +1 more source

Treponema pallidum Protein Tp0136 Induces Spheroidization of Vascular Endothelial Cells, Resulting in Widened Intercellular Junctions and Enhanced Vascular Permeability

Small Science, EarlyView.
Treponema pallidum protein Tp0136 enhances vascular permeability by upregulating CSRP1, which induces MYO10 exon 19 skipping, reducing MYO10 expression and triggering endothelial spheroidization. This study reveals a novel RNA splicing‐mediated dissemination mechanism, proposing CSRP1/MYO10 as therapeutic targets to limit bacterial dissemination in ...
Yu Lin, Xi Luo, Xu Shen, Xiao‐Lin Fu, Li‐Rong Lin, Tian‐Ci Yang   +5 more
wiley   +1 more source

Washington University Medical Alumni Quarterly, April 1942 [PDF]

, 1942

core   +1 more source

Intrapartum antibiotic prophylaxis to prevent Group B streptococcal infections in newborn infants: a systematic review and meta-analysis comparing various strategies. [PDF]

EClinicalMedicine
Panneflek TJR, Hasperhoven GF, Chimwaza Y, Allen C, Lavin T, Te Pas AB, Bekker V, van den Akker T.   +7 more
europepmc   +1 more source

Targeted siRNA Delivery Using Cetuximab‐Conjugated Starch for Epidermal Growth Factor Receptor‐Driven Head and Neck Squamous Cell Carcinoma

Small Science, EarlyView.
A starch‐based carrier conjugated to cetuximab enables targeted siRNA delivery to epidermal growth factor receptor‐overexpressing tumors. The complexes exhibit dual passive and active tumor targeting, effective cellular uptake, and gene silencing, offering a versatile platform for RNA therapeutics in head and neck cancer.
Chen Benafsha, Limor Cohen, Leah Shimonov, Riki Goldbart, Tamar Traitel, Eliz Amar‐Lewis, Ramesh Chintakunta, Manu Parasad, Uzi Hadad, Moshe Elkabets, Joseph Kost   +10 more
wiley   +1 more source

Editorial: When streptococci seize the opportunity: identifying how manipulation of host inflammatory signaling impacts pathogenesis in streptococcal infections. [PDF]

Front Cell Infect Microbiol
Flaherty RA, Lee SW, Manning SD.
europepmc   +1 more source

Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections

Small Science, EarlyView.
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton, Richard Bright, Vi Khanh Truong, Krasimir Vasilev   +3 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

Small Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han, Jieyun Xu, Xinyu Guo, Lingyu Liang, Linjun Zhang, Yu Su, Wendong Gao, Qingming Tang, Lili Chen, Zhuofan Chen, Yin Xiao, Zetao Chen   +11 more
wiley   +1 more source

Gut Microbiota as a Mediator Between Intestinal Fibrosis and Creeping Fat in Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Intestinal stricture remains one of the most challenging complications in Crohn's disease, and its underlying mechanisms are poorly understood. Accumulating evidence suggests that gut microbiota is significantly altered in stenotic intestines and may play a key role in the development of fibrogenesis in Crohn's disease.
Caiguang Liu, Rongchang Li, Jing Nie, Jinshen He, Zihao Lin, Xiaomin Wu, Jinyu Tan, Zishan Liu, Longyuan Zhou, Xiaozhi Li, Zhirong Zeng, Minhu Chen, Shixian Hu, Yijun Zhu, Ren Mao   +14 more
wiley   +1 more source