Results 41 to 50 of about 56,561 (304)

Endolysins against Streptococci as an antibiotic alternative

Frontiers in Microbiology, 2022
Multi-drug resistance has called for a race to uncover alternatives to existing antibiotics. Phage therapy is one of the explored alternatives, including the use of endolysins, which are phage-encoded peptidoglycan hydrolases responsible for bacterial ...
Kuan Yee Wong, Megat Hamzah Megat Mazhar Khair, Adelene Ai-Lian Song, Mas Jaffri Masarudin, Chou Min Chong, Lionel Lian Aun In, Michelle Yee Mun Teo   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP

BMJ Medicine
Objective To investigate the effect of the covid-19 pandemic on the number of patients with group A streptococcal infections and related antibiotic prescriptions.Design Retrospective cohort study in England using OpenSAFELY-TPP.Setting Primary care ...
Ben Goldacre, David Evans, Sam Harper, Richard Croker, Christopher Wood, Brian MacKenna, Elizabeth Beech, Chris Bates, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, John Parry, Frank Hester, Kieran Hand, Helen Curtis, Rose Higgins, Andrew D Brown, Simon Davy, George Hickman, Tom Ward, Rebecca M Smith, Louis Fisher, Iain Dillingham, Steven Maude, Lucy Bridges, Christine Cunningham, Victoria Speed, Ben FC Butler-Cole, Sebastian CJ Bacon, Thomas O'Dwyer, Liam C Hart   +30 more
doaj   +1 more source

Streptococcal Infection: Issues of Pathogenesis, Role in the Formation of Somatic Pathology in Children

Aktualʹnaâ Infektologiâ, 2014
Streptococcal infections are the most common diseases of bacterial origin. Major importance in human pathology belongs to streptococci serogroup A. There are primary, secondary and rare forms of streptococcal infection.
Ye.V. Prokhorov, L.L. Chelpan
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Streptococcal A Infection

Journal of Perinatal & Neonatal Nursing, 2009
Streptococcal A infections are reemerging as a dangerous clinical problem. This particular infection is usually a problem for the postpartum mother and not usually associated with fetal or neonatal infections. Maternal morbidity and mortality are overwhelming when compared with other maternal infections.
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Streptococcal Toxic-Shock Syndrome: Spectrum of Disease, Pathogenesis, and New Concepts in Treatment

Emerging Infectious Diseases, 1995
Since the 1980s there has been a marked increase in the recognition and reporting of highly invasive group A streptococcal infections with or without necrotizing fasciitis associated with shock and organ failure.
Dennis L. Stevens
doaj   +1 more source

SG-APSIC1155: Drug susceptibility patterns of fulminant group G Streptococcus (GGS) infection as a re-emerging infectious disease in Japan

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Objectives: Severe streptococcal infections are invasive, re-emerging infections that rapidly worsen and lead to death. Not only group A Streptococcus (GAS) but also group g Streptococcus (GGS) are the causative agents of this infection.
Masaaki Minami, Ryoko Sakakibara, Shunsuke Akahori   +2 more
doaj   +1 more source

THE RENAL RESPONSE TO STREPTOCOCCAL INFECTION

Medicine, 1970
Excerpt A prospective study was conducted on patients with streptococcal infection to determine the prevalence and degree of renal involvement as compared and contrasted with classical clinical acu...
P, Freedman, H P, Meister, H J, Lee, E C, Smith, B S, So, B D, Nidus   +5 more
openaire   +2 more sources