Results 31 to 40 of about 77,860 (302)

Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus [PDF]

, 2017
Background: A group A Streptococcus (GAS) lineage of genotype emm3, sequence type 15 (ST15) was associated with a six month upsurge in invasive GAS disease in the UK.
Afshar, B, Al-Shahib, A, Efstratiou, A, Holden, M T G, Lamagni, T L, Smith, K C, Sriskandan, S, Turner, C E, Underwood, A   +8 more
core   +3 more sources

An update on environmental mastitis: challenging perceptions [PDF]

, 2017
Environmental mastitis is the most common and costly form of mastitis in modern dairy herds where contagious transmission of intramammary pathogens is controlled through implementation of standard mastitis prevention programmes.
Klaas, I.C., Zadoks, R.N.
core   +1 more source

The development of a 16S rRNA gene based PCR for the identification of Streptococcus pneumoniae and comparison with four other species specific PCR assays [PDF]

, 2010
Background: Streptococcus pneumoniae is one of the most frequently encountered pathogens in humans but its differentiation from closely related but less pathogenic streptococci remains a challenge.
Nabil Abdullah El Aila, Stefan Emler, Tarja Kaijalainen, Thierry De Baere, Bart Saerens, Elife Alkan, Pieter Deschaght, Rita Verhelst, Mario Vaneechoutte, A Ortqvist, L Spanjaard, D Rozkiewicz, JC Arbique, CA Dias, S Nunes, SI Aguiar, T Kaijalainen, N Suzuki, TO Messmer, R Verhelst, T Kaijalainen, G Carvalho Mda, GM Abdeldaim, M Vaneechoutte, S Rintamaki, KE Morrison, D Llull, JC McAvin, N Suzuki, ER Keith, RW Bentley   +30 more
core   +3 more sources

The prognosis of streptococcal prosthetic bone and joint infections depends on surgical management—A multicenter retrospective study

International Journal of Infectious Diseases, 2019
Background: The optimal treatment of streptococcal prosthetic joint infections (PJIs) is unclear. Methods: A cohort of streptococcal PJIs was reviewed retrospectively in seven reference centers for the management of complex bone and joint infections ...
Rafael Mahieu, Vincent Dubée, Valérie Seegers, Carole Lemarié, Séverine Ansart, Louis Bernard, Gwenaël Le Moal, Nathalie Asseray, Cédric Arvieux, Céline Ramanantsoa, Hélène Cormier, Erick Legrand, Pierre Abgueguen   +12 more
doaj   +1 more source

Endolysins against Streptococci as an antibiotic alternative

Frontiers in Microbiology, 2022
Multi-drug resistance has called for a race to uncover alternatives to existing antibiotics. Phage therapy is one of the explored alternatives, including the use of endolysins, which are phage-encoded peptidoglycan hydrolases responsible for bacterial ...
Kuan Yee Wong, Megat Hamzah Megat Mazhar Khair, Adelene Ai-Lian Song, Mas Jaffri Masarudin, Chou Min Chong, Lionel Lian Aun In, Michelle Yee Mun Teo   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP

BMJ Medicine
Objective To investigate the effect of the covid-19 pandemic on the number of patients with group A streptococcal infections and related antibiotic prescriptions.Design Retrospective cohort study in England using OpenSAFELY-TPP.Setting Primary care ...
Ben Goldacre, David Evans, Sam Harper, Richard Croker, Christopher Wood, Brian MacKenna, Elizabeth Beech, Chris Bates, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, John Parry, Frank Hester, Kieran Hand, Helen Curtis, Rose Higgins, Andrew D Brown, Simon Davy, George Hickman, Tom Ward, Rebecca M Smith, Louis Fisher, Iain Dillingham, Steven Maude, Lucy Bridges, Christine Cunningham, Victoria Speed, Ben FC Butler-Cole, Sebastian CJ Bacon, Thomas O'Dwyer, Liam C Hart   +30 more
doaj   +1 more source

Streptococcal Infection: Issues of Pathogenesis, Role in the Formation of Somatic Pathology in Children

Aktualʹnaâ Infektologiâ, 2014
Streptococcal infections are the most common diseases of bacterial origin. Major importance in human pathology belongs to streptococci serogroup A. There are primary, secondary and rare forms of streptococcal infection.
Ye.V. Prokhorov, L.L. Chelpan
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

SG-APSIC1155: Drug susceptibility patterns of fulminant group G Streptococcus (GGS) infection as a re-emerging infectious disease in Japan

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Objectives: Severe streptococcal infections are invasive, re-emerging infections that rapidly worsen and lead to death. Not only group A Streptococcus (GAS) but also group g Streptococcus (GGS) are the causative agents of this infection.
Masaaki Minami, Ryoko Sakakibara, Shunsuke Akahori   +2 more
doaj   +1 more source