Results 71 to 80 of about 3,345,269 (394)

Tics, OCD and Streptococcal Infection (PANDAS)

Pediatric Neurology Briefs, 2008
Forty matched pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) case-control pairs were prospectively evaluated clinically and with testing for group A b-hemolytic streptococcus for an average of 2 years ...
J Gordon Millichap
doaj   +1 more source

The Association between Invasive Group A Streptococcal Diseases and Viral Respiratory Tract Infections

Frontiers in Microbiology, 2016
Viral infections of the upper respiratory tract are associated with a variety of invasive diseases caused by Streptococcus pyogenes, the group A streptococcus, including pneumonia, necrotizing fasciitis, toxic shock syndrome, and bacteremia.
Andrea L. Herrera, Victor C. Huber, M. Chaussee   +2 more
semanticscholar   +1 more source

Effect of case management on neonatal mortality due to sepsis and pneumonia. [PDF]

, 2011
BACKGROUND: Each year almost one million newborns die from infections, mostly in low-income countries. Timely case management would save many lives but the relative mortality effect of varying strategies is unknown.
Bhutta, Zulfiqar A, Black, Robert, Cousens, Simon, Ganatra, Hammad A, Lawn, Joy E, Lee, Anne CC, Syed, Sana, Zaidi, Anita KM   +7 more
core   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection. [PDF]

, 2019
Streptococcus gordonii and Streptococcus sanguinis are primary colonizers of the tooth surface. Although generally non-pathogenic in the oral environment, they are a frequent cause of infective endocarditis.
Barnard, Karen N, Bensing, Barbara A, Iverson, TM, Lebrilla, Carlito B, Li, Liang, Parrish, Colin R, Sullam, Paul M, Thomas, Wendy E, Wong, Maurice, Xiong, Yan, Yakovenko, Olga   +10 more
core   +3 more sources

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

PREVALENCE OF STREPTOCOCCAL PHARYNGITIS AMONG SCHOOL CHILDREN OF POKHARA VALLEY, NEPAL

Journal of Nepal Medical Association, 2003
Group A Beta Haemolytic Streptococcal (GABHS) infections and their sequelae Rheumatic fever (RF) and Glomerulonephritis (GN) have a world wide distribution and pose an important health problem.
Lochana Shrestha, J B Khattri, K N Brahmadathan, J S Nagra   +3 more
doaj   +1 more source

Biofilm in group A streptococcal necrotizing soft tissue infections.

JCI Insight, 2016
Necrotizing fasciitis caused by group A streptococcus (GAS) is a life-threatening, rapidly progressing infection. At present, biofilm is not recognized as a potential problem in GAS necrotizing soft tissue infections (NSTI), as it is typically linked to ...
N. Siemens, B. Chakrakodi, S. Shambat, M. Morgan, H. Bergsten, O. Hyldegaard, S. Skrede, P. Arnell, M. Madsen, L. Johansson, J. Juarez, L. Bosnjak, M. Mörgelin, M. Svensson, A. Norrby-Teglund   +14 more
semanticscholar   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source