Results 61 to 70 of about 12,364 (218)

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang   +3 more
wiley   +1 more source

Onosma armenum Extract Loaded Mesoporous Silica Nanoparticles for the Prevention of Biofilm‐Associated Infections

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
Bioactive mesoporous silica nanoparticles (MSNPs) loaded with O. armenum extract were developed to evaluate their antibiofilm activity against biofilm‐forming Staphylococcus aureus ATCC 25923. The phytochemical content of the extract was analyzed via liquid chromatography–electrospray ionization tandem mass spectrometry.
Sevim Feyza Erdoğmuş   +3 more
wiley   +1 more source

Toxic Shock Syndrome: A Literature Review

open access: yesAntibiotics
Toxic shock syndrome (TSS) is a rare, life-threatening, toxin-mediated infectious process linked, in the vast majority of cases, to toxin-producing strains of Staphylococcus aureus or Streptococcus pyogenes.
Enora Atchade   +4 more
doaj   +1 more source

Streptococcal Infection: Issues of Pathogenesis, Role in the Formation of Somatic Pathology in Children

open access: yesAktualʹnaâ Infektologiâ, 2014
Streptococcal infections are the most common diseases of bacterial origin. Major importance in human pathology belongs to streptococci serogroup A. There are primary, secondary and rare forms of streptococcal infection.
Ye.V. Prokhorov, L.L. Chelpan
doaj   +1 more source

A case report of streptococcal toxic shock syndrome caused by Streptococcus mitis in a healthy adult

open access: yesBMC Infectious Diseases, 2021
Background Streptococcal toxic shock syndrome (STSS) is an acute, multisystem and toxin-mediated disease that usually causes shock and multiple organ failure in the early stages of its clinical course.
Xiang Chen, Ying Ying Gong, Li Zhang
doaj   +1 more source

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

open access: yesSmall, Volume 22, Issue 22, 17 April 2026.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu   +25 more
wiley   +1 more source

Familial Transmission of a Serious Disease—Producing Group A Streptococcus Clone: Case Reports and Review [PDF]

open access: yes, 2017
Invasive group A streptococcus (GAS) infections are emerging diseases; however, person-to-person transmission of invasive GAS producing life-threatening infection has been observed rarely.
DiPersio, J.   +10 more
core  

Clinical and pathophysiological aspects of sepsis [PDF]

open access: yes, 2014
Severe sepsis and septic shock represent challenging problems for the health care system. Despite adequate antibiotics and modern intensive care, severe sepsis is associated with a substantial mortality rate of around 30%, which rises even higher if ...
Linnér, Anna
core   +1 more source

Severe group a streptococcal infection and streptococcal toxic shock syndrome [PDF]

open access: yesCanadian Journal of Anesthesia/Journal canadien d'anesthésie, 2000
To review the literature on group A streptococcal toxic shock syndrome, (STSS).Medline and EMBASE searches were conducted using the key words group A streptococcal toxic shock syndrome, alone and in combination with anesthesia; and septic shock, combined with anesthesia.
F, Baxter, J, McChesney
openaire   +2 more sources

Primary Streptococcal Peritonitis in a Postpartum Patient: A Rare but Life‐Threatening Condition

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT We present the case of a 43‐year‐old postpartum woman who developed primary streptococcal peritonitis with a fulminant septic course requiring intensive care. Initial symptoms were nonspecific and improved temporarily, but the patient returned the next day with recurrent pain and markedly elevated inflammatory markers.
Matthias Pimiskern, Helmut Trimmel
wiley   +1 more source

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