Results 281 to 290 of about 773,029 (383)

Optimized Machine Learning for Autonomous Enzymatic Reaction Intensification in a Self‐Driving Lab

open access: yesBiotechnology and Bioengineering, EarlyView.
A machine learning‐powered self‐driving lab accelerates enzymatic reaction optimization by autonomously navigating complex parameter spaces. Through over 10,000 simulated campaigns, we identified an optimal algorithm for efficient, automated optimization.
Sebastian Putz   +5 more
wiley   +1 more source

A Highly Arginolytic Streptococcus Species That Potently Antagonizes Streptococcus mutans

open access: yesApplied and Environmental Microbiology, 2016
Xuelian Huang   +6 more
semanticscholar   +1 more source

Restoration of human tooth enamel

open access: yesBMEMat, EarlyView.
Human tooth enamel has remarkable properties but lacks self‐repair ability. Existing restorative materials cannot fully replicate enamel's microstructure and function, resulting in low restorative efficiency. This review summarizes the formation process and characteristics of enamel, and current restorative materials and future research directions are ...
Hanlin Liu   +10 more
wiley   +1 more source

Contribution of a LysM domain-containing protein regulated by VicRK to <i>Streptococcus sanguinis</i> virulence. [PDF]

open access: yesVirulence
Franco EM   +8 more
europepmc   +1 more source

Continuous purification of a parvovirus using two aqueous two‐phase extraction steps

open access: yesBiotechnology Progress, EarlyView.
Abstract Aqueous two‐phase systems (ATPS) are a liquid–liquid extraction method that offers low‐cost, continuous‐adaptable virus purification. A two‐step ATPS using polyethylene glycol (PEG) and sodium citrate that recovered 66% of infectious porcine parvovirus with 2.0 logs of protein removal and 1.0 logs of DNA removal in batch has now been run ...
Natalie M. Nold   +11 more
wiley   +1 more source

Minimizing batch‐to‐batch variability of a live virus vaccine by process analytical technologies

open access: yesBiotechnology Progress, EarlyView.
Abstract For bioprocesses producing live virus, such as enterovirus Coxsackievirus A21, viral titer (infectivity basis) decay rates can exceed 30% within a day. Consequently, harvest timing is paramount. To optimize titer at harvest, a continuous viral product titer model was generated to elucidate kinetics.
Katherine Forrester   +4 more
wiley   +1 more source

The epidemiology of infectious meningitis in Ghana: a systematic review and meta-analysis. [PDF]

open access: yesBMC Public Health
Akwetey SA   +6 more
europepmc   +1 more source

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