Results 31 to 40 of about 355,432 (267)

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

A case of phlegmonous gastritis complicated by stomach necrosis requiring gastrectomy

open access: yesGastroenterology & Endoscopy
Phlegmonous Gastritis (PG) is a rare and swiftly progressing disease that is often fatal. It typically involves severe invasion of the gastric wall by bacteria. Due to its vague symptoms, diagnosis is often delayed.
Karimulla S. Shaik   +6 more
doaj   +1 more source

From Streptococcal Pharyngitis/Tonsillitis to Myocarditis: A Systematic Review

open access: yesJournal of Cardiovascular Development and Disease, 2022
(1) Background: Myocarditis following group A streptococcal pharyngitis and tonsillitis is a relatively rare medical condition. The aim of this systematic review was to identify specific ECG changes, laboratory parameters and signs, and symptoms ...
Lukas Schmutzler   +3 more
doaj   +1 more source

STREPTOCOCCUS PNEUMONIA [PDF]

open access: yesJournal of the American Medical Association, 1919
n ...
openaire   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Investigation of in vitro Mineral Forming Bacterial Isolates from Subgingival Calculus

open access: yesArchives of Clinical and Experimental Surgery, 2014
The mechanism that dictates the formation of dental calculus, an important component of periodontal health, has yet to be sufficiently explained. The effect of bacterial flora on dental calculus formation is important for periodontal status.
Turgut Demir, Ozlem Baris, Esra Zor
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

FATAL GROUP A STREPTOCOCCAL TOXIC SHOCK-LIKE SYNDROME IN A CHILD WITH VARICELLA: REPORT OF THE FIRST WELL DOCUMENTED CASE WITH DETECTION OF THE GENETIC SEQUENCES THAT CODE FOR EXOTOXINS SPE A AND B, IN SÃO PAULO, BRAZIL

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1999
A previously healthy seven-year-old boy was admitted to the intensive care unit because of toxaemia associated with varicella. He rapidly developed shock and multisystem organ failure associated with the appearance of a deep-seated soft tissue infection ...
Jaques SZTAJNBOK   +5 more
doaj  

A role of oropharyngeal microbiota in developing acute and chronic diseases of the upper respiratory tract

open access: yesИнфекция и иммунитет, 2020
Currently, a rise in incidence of polyethological inflammation of the upper respiratory tract mucosa paralleled by altered resident and transient microbiota displaying in many cases increased antibiotic resistance has been noted.
I. I. Ababii   +7 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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