Results 51 to 60 of about 480,499 (310)

The identification of Streptococcus pneumoniae [PDF]

open access: yes, 2006
ei tietoa saavutettavuudesta unknown ...
Kaijalainen, Tarja
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Camel Streptococcus agalactiae populations are associated with specific disease complexes and acquired the tetracycline resistance gene tetM via a Tn916-like element [PDF]

open access: yes, 2013
Camels are the most valuable livestock species in the Horn of Africa and play a pivotal role in the nutritional sustainability for millions of people.
Mario Younan   +41 more
core   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Aronson Streptococcus [PDF]

open access: yesJournal of Hygiene, 1935
The characters of the Aronson Streptococcus from Prof. Neufeld's laboratory at the “Robert Koch” Institute in Berlin have been described. This coccus resembles the pneumococcus in many respects, viz. the appearance of the colonies on the surface of horse blood agar, its virulence and capsule production in mice and rabbits, the production of a specific ...
openaire   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Post-Streptococcal Uveitis

open access: yesJournal of Ophthalmology, 2020
Post-streptococcal uveitis refers to the most severe inflammatory conditions of the eye. It often affects young people leading to incapacity for work and physical disability.
Konovalova N.V.   +6 more
doaj   +1 more source

Genome analysis of a highly virulent serotype 1 strain of streptococcus pneumoniae from West Africa [PDF]

open access: yes, 2012
Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and bacteremia, estimated to cause 2 million deaths annually. The majority of pneumococcal mortality occurs in developing countries, with serotype 1 a leading cause in these areas.
Loman Nicholas J.   +43 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A case of phlegmonous gastritis complicated by stomach necrosis requiring gastrectomy

open access: yesGastroenterology & Endoscopy
Phlegmonous Gastritis (PG) is a rare and swiftly progressing disease that is often fatal. It typically involves severe invasion of the gastric wall by bacteria. Due to its vague symptoms, diagnosis is often delayed.
Karimulla S. Shaik   +6 more
doaj   +1 more source

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