Results 71 to 80 of about 355,432 (267)

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

Advanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang, Yuxiang Ren, Shofarul Wustoni, Atheer Alqatari, Adel Hama, Yazhou Wang, Long Chen, Jessica Parrado Agudelo, Luca Salvigni, Keying Guo, Ashraf Dada, Stefan T. Arold, Raik Grünberg, Sahika Inal   +13 more
wiley   +1 more source

The effects of probiotics intervention on oral health outcomes: a comprehensive umbrella review of meta-analyses

Frontiers in Oral Health
BackgroundProbiotics are proposed adjuncts for oral health, but findings from meta-analyses are inconsistent. We conducted an umbrella review of meta-analyses to synthesize evidence on probiotics’ effects on cariogenic bacteria such as Streptococus (S ...
Zhen Tang, Yunzhen Deng, Gang Guo, LiLi Zhou   +3 more
doaj   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

Detection of streptococcal deoxyribonucleic acid with polymerase chain reaction in excised valvular tissue of rheumatic heart disease patients

Annals of Pediatric Cardiology
Introduction: Rheumatic heart disease (RHD) is traditionally attributed to cumulative valvular injury from the recurrent episodes of acute rheumatic fever.
Nitin Kumar Parashar, Mohsin Raj Mantoo, Sudheer Arava, Sivasubramanian Ramakrishnan, Palleti Rajashekar, Mumun Sinha, Sandeep Seth, Balram Bhargava   +7 more
doaj   +1 more source

In vitro antimicrobial effect of palm oils rich in medium-chain fatty acids against mastitis-causing Gram-positive bacteria

Czech Journal of Animal Science, 2019
Various pathogens causing mastitis in dairy cattle are of serious concern due to their increasing antibacterial resistance and potential transmission to other cows, calves, and the environment, especially through the milking process.
Klára Laloučková, Lucie Malá, Paula Slaničková, Eva Skřivanová   +3 more
doaj   +1 more source

Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method

Advanced Science, EarlyView.
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas, Daniëlle C. A. Duffhues, Pim van den Bersselaar, Sarah Pragnere, Bart G. W. Groenen, Mariana Azevedo Gonzalez Oliva, Giuseppe Ciccone, Manuel Salmeron‐Sanchez, Carlijn V. C. Bouten, Jose J. Muñoz, Vito Conte   +10 more
wiley   +1 more source

Role of epidemiological risk factors in improving the clinical diagnosis of streptococcal sore throat in pediatric clinical practice

Journal of Family Medicine and Primary Care, 2019
Background and Aims: Antibiotics are frequently prescribed for sore throat in developing countries, that in turn leads to huge healthcare expenditure and their irrational use may lead to antimicrobial resistance in the community. The aim of this study is
Kapil Bhalla, Parveen Bhardwaj, Ashish Gupta, Shuchi Mehra, Deepak Nehra, Sanjiv Nanda   +5 more
doaj   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Atypical Palmar Involvement with Erythema Elevatum Diutinum as a Sole Manifestation: A Report of Two Cases

Clinical, Cosmetic and Investigational Dermatology, 2020
Ghadah I ALHetheli,1 Ohoud Z Aljarbou,2 Ahmed ALHumidi,3 Mohammed I AlJasser4 1Division of Dermatology, College of Medicine, Qassim University, Buraidah, Saudi Arabia; 2Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Riyadh,
ALHetheli GI, Aljarbou OZ, ALHumidi A, AlJasser MI   +3 more
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