Results 71 to 80 of about 829,176 (345)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Post-Streptococcal Uveitis

open access: yesJournal of Ophthalmology, 2020
Post-streptococcal uveitis refers to the most severe inflammatory conditions of the eye. It often affects young people leading to incapacity for work and physical disability.
Konovalova N.V.   +6 more
doaj   +1 more source

Streptococcus sanguinis biofilm formation & interaction with oral pathogens

open access: yesFuture Microbiology, 2018
Caries and periodontitis are the two most common human dental diseases and are caused by dysbiosis of oral flora. Although commensal microorganisms have been demonstrated to protect against pathogens and promote oral health, most previous studies have ...
Bin Zhu   +3 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Genome comparison and physiological characterization of eight Streptococcus thermophilus strains isolated from Italian dairy products [PDF]

open access: yes, 2017
Eight Streptococcus thermophilus strains of dairy origin isolated in Italy were chosen to investigate autochthonous bacterial diversity in this important technological species. In the present study a comparative analysis of all the 17 S.
Campanaro, Stefano   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A case of phlegmonous gastritis complicated by stomach necrosis requiring gastrectomy

open access: yesGastroenterology & Endoscopy
Phlegmonous Gastritis (PG) is a rare and swiftly progressing disease that is often fatal. It typically involves severe invasion of the gastric wall by bacteria. Due to its vague symptoms, diagnosis is often delayed.
Karimulla S. Shaik   +6 more
doaj   +1 more source

Preterm Birth Associated With Group B Streptococcus Maternal Colonization Worldwide: Systematic Review and Meta-analyses

open access: yesClinical Infectious Diseases, 2017
Complications of preterm birth are the leading cause of deaths in children aged
Fiorella Bianchi-Jassir   +16 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Investigation of in vitro Mineral Forming Bacterial Isolates from Subgingival Calculus

open access: yesArchives of Clinical and Experimental Surgery, 2014
The mechanism that dictates the formation of dental calculus, an important component of periodontal health, has yet to be sufficiently explained. The effect of bacterial flora on dental calculus formation is important for periodontal status.
Turgut Demir, Ozlem Baris, Esra Zor
doaj   +1 more source

Home - About - Disclaimer - Privacy