Results 71 to 80 of about 439,224 (315)

Serotypes and antimicrobial resistance of meningeal isolates of Streptococcus pneumonia. Cuba, 2007-2012

VacciMonitor, 2014
An observational study was conducted to know the serotypes and antimicrobial susceptibility of isolates of Streptococcus pneumoniae responsible for meningitis in Cuba, where there is no vaccine yet to prevent invasive pneumococcal disease.
Gilda Toraño-Peraza, Lisania Pías-Solis, Miriam Abreu-Capote, Misladys Rodríguez-Ortega, Félix Dickinson- Meneses, Marlen Varcárcel-Sánchez   +5 more
doaj  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2

, 2002
In the present study we investigated the role of the fibronectin (FN)- and fibrinogen (FGN)-binding protein (FBPS) in the pathogenesis of Streptococcus suis serotype 2 in piglets. The complete gene encoding FBPS from S.
Dijkstra, J., Smit, H.E., Verhaar, R., Alphen, L., van, Greeff, A., de, Robin Verhaar, Loek van Alphen, Herma Buys, Buys, H., Janny Dijkstra, Hilde E. Smith, Astrid de Greeff   +11 more
core   +1 more source

Whole genome investigation of a divergent clade of the pathogen Streptococcus suis [PDF]

, 2015
This work was supported by a Longer and Larger (LoLa) grant from the Biotechnology and Biological Sciences Research Council (grant numbers BB/G020744/1, BB/G019177/1, BB/G019274/1, and BB/G003203/1), the UK Department for Environment, Food and Rural ...
Langford, P.R., Paul eLangford, Tucker, AW, Weinert, LA, Alexander W. Tucker, Baig, A., Peters, S.E., Rycroft, A.N., Tucker, A.W., Holden, Matthew T G, Wang, J., Howell, K.J., Peters, SE, Parkhill, J, Consortium, B., Wren, B.W., Tucker, Alexander W, Matthew T.G. Holden, Peters, S E, Langford, PR, Julian eParkhill, Roy R Chaudhuri, Sarah E Peters, Lucy A. Weinert, Andrew eRycroft, Wren, BW, Baig, A, Holden, M T G, Wren, B W, Jinhong eWang, Paul R. Langford, Alexander W Tucker, Wang, Jinhong, Maskell, DJ, Langford, Paul R, Holden, M.T.G., Abiyad Baig, Abiyad eBaig, Brendan W Wren, Holden, MTG, Maskell, Duncan J, Chaudhuri, RR, Rycroft, Andrew N, Rycroft, AN, Kate J. Howell, Tucker, A W, Weinert, Lucy A, Wren, Brendan W, Duncan J Maskell, Andrew N. Rycroft, BRaDP1T Consortium, Kate J Howell, Chaudhuri, R R, Peters, Sarah E, Holden, Matthew TG, Wang, J, Howell, K J, Duncan J. Maskell, Parkhill, J., Chaudhuri, Roy R, Roy R. Chaudhuri, Brendan W. Wren, Weinert, L.A., Baig, Abiyad, Rycroft, A N, Lucy A Weinert, Julian Parkhill, Matthew T. G. Holden, Maskell, D.J., Howell, Kate J, Parkhill, Julian, Maskell, D J, Sarah E. Peters, Weinert, L A, Howell, KJ, Langford, P R, Jinhong Wang, Chaudhuri, R.R.   +77 more
core   +1 more source

Association of Novel Streptococcus sanguinis Virulence Factors With Pathogenesis in a Native Valve Infective Endocarditis Model

Frontiers in Microbiology, 2020
Streptococcus sanguinis (S. sanguinis) is an abundant oral commensal which can cause disseminated human infection if it gains access to the bloodstream. The most important among these diseases is infective endocarditis (IE). While virulence phenotypes of
Anthony M. Martini, Bridget S. Moricz, Allison K. Ripperger, Phuong M. Tran, Molly E. Sharp, Ana N. Forsythe, Katarina Kulhankova, Wilmara Salgado-Pabón, Bradley D. Jones, Bradley D. Jones   +9 more
doaj   +1 more source

Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation [PDF]

, 2012
Streptococcus pyogenes M/emm3 strains have been epidemiologically linked with enhanced infection severity and risk of streptococcal toxic shock syndrome (STSS), a syndrome triggered by superantigenic stimulation of T cells. Comparison of S.
McGregor, Karen, Davies, F.J., Frances J Davies, Chong, Deborah L. W., McGregor, K., Davies, Frances J., McGregor, K, Leili Farzaneh, Spratt, BG, Leili Farzaneh (130255), Pichon, B., Shiranee Sriskandan, Efstratiou, A, McGregor Karen, Bruno Pichon (130249), Pichon, B, Holden, Matthew T. G., Davies, FJ, Mary Sommerlad, Androulla Efstratiou, Turner, CE, Sommerlad, M, Chong, DLW, Sriskandan Shiranee, Mary Sommerlad (130242), Sommerlad, M., Turner Claire E., Farzaneh, L., Brian G Spratt, Deborah L. W. Chong (130252), Brian G. Spratt (10001), Sriskandan, Shiranee, Holden, M.T., Holden, MTG, Matthew T G Holden, Sriskandan, S., Androulla Efstratiou (130260), Sommerlad Mary, Matthew T. G. Holden (130258), Pichon Bruno, Frances J. Davies (130247), Spratt, B.G., Shiranee Sriskandan (16154), Holden Matthew T. G., Karen McGregor (130245), Chong Deborah L. W., Turner, C.E., Karen McGregor, Sommerlad, Mary, Farzaneh, L, Sriskandan, S, Claire E Turner, Davies Frances J., Pichon, Bruno, Efstratiou, A., Farzaneh, Leili, Spratt Brian G., Claire E. Turner (130239), Spratt, Brian G., Efstratiou, Androulla, Efstratiou Androulla, Chong, D.L., Deborah L W Chong, Bruno Pichon, Farzaneh Leili, Turner, Claire E.   +65 more
core   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

A cluster of pediatric VITT-like cases with thrombosis and thrombocytopenia following respiratory infections-Case series

Research and Practice in Thrombosis and Haemostasis
Background: Adenoviral vector COVID-19 vaccine-induced immune thrombotic thrombocytopenia (VITT) is a heparin-independent platelet-activating disorder. An increasing number of VITT-like disorders without previous vaccination are being identified.
Dimitra Dimopoulou, Lida Mentesidou, Athina Dettoraki, Christina Karastathi, Maria Berikopoulou, Panagiota Katsouli, Ioanna Anastasopoulou, Iason G. Stamatakis, Theodora Bachou, Flora Tzifi, Aikaterini Michalopoulou, Anna Messaritaki, Vana Spoulou, Helen Pergantou   +13 more
doaj   +1 more source

Lung abscess in immunocompromised

Galicia Clínica, 2020
We present the case of a 44-year-old man, construction worker, hypertensive, smoker, with rheumatoid arthritis under prednisolone 10mg/day for 10 months. Gingival crevice disease. The patient was referred to the Emergency Department after 5 days of right
Teresa Margarida Dias Moreira, Ligía Rodrigues dos Santos   +1 more
doaj   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source