FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Determination of Certain Immunological and Physicochemical Features of Pneumococcal Surface Protein A (PspA): In-silico Cloning of pspA [PDF]
Modern MedicineObjective: Pneumococcal surface protein A (PspA) is present in almost all strains of pneumococci and is highly immunogenic, stimulating the production of antibodies. It has a role in pneumococcal pathogenicity.
Enass Waad AL-HADIDI, Ali Adel DAWOOD
doaj +1 more source
The well-coordinated linkage between acidogenicity and aciduricity via insoluble glucans on the surface of Streptococcus mutans. [PDF]
, 2015 Streptococcus mutans is considered the principal cariogenic bacterium for dental caries. Despite the recognition of their importance for cariogenesis, the possible coordination among S.
Guo, Lihong +4 more
core +1 more source
Quorum Sensing Regulation of Competence and Bacteriocins in Streptococcus pneumoniae and mutans
Genes, 2017 The human pathogens Streptococcus pneumoniae and Streptococcus mutans have both evolved complex quorum sensing (QS) systems that regulate the production of bacteriocins and the entry into the competent state, a requirement for natural transformation ...
Erin Shanker, Michael J. Federle
semanticscholar +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
, 2009 Das Ziel dieser Arbeit war die Analyse der Forschungsergebnisse zu den Streptokokken unter szientometrischen Gesichtspunkten, die in einem Zeitraum von 50 Jahren veröffentlicht worden sind (1957-2006). Dafür wurden die Datenbanken „ISI-Web of Science“ des „Thomson Scientific Institute“ und „PubMed“ der „United States National Library of Medicine“ unter
Mark van der Linden +4 more
openaire +2 more sources
VacciMonitor, 2014 An observational study was conducted to know the serotypes and antimicrobial susceptibility of isolates of Streptococcus pneumoniae responsible for meningitis in Cuba, where there is no vaccine yet to prevent invasive pneumococcal disease.
Gilda Toraño-Peraza +5 more
doaj
Neutrophil and lymphocyte responses to oral Streptococcus in Adamantiades-Behcet's disease [PDF]
, 2005 Immune reactions against microorganisms play an important pathogenic role in Adamantiades-Behçet’s disease (ABD). We had previously obtained Streptococcus sanguinis (strain BD113-20) isolated from the oral cavity of patients with ABD.
Aoki +30 more
core +1 more source
Stillbirth With Group B Streptococcus Disease Worldwide: Systematic Review and Meta-analyses
Clinical Infectious Diseases, 2017 Group B Streptococcus (GBS) is associated with invasive disease in utero and stillbirth. We estimated that 1% of all stillbirths in developed countries and 4% in Africa were associated with GBS.
Anna C. Seale +22 more
semanticscholar +1 more source
Developing a serocorrelate of protection against invasive group B streptococcus disease in pregnant women: a feasibility study. [PDF]
, 2019 BACKGROUND: Group B streptococcus is the leading cause of infection in infants. Currently, intrapartum antibiotic prophylaxis is the major strategy to prevent invasive group B streptococcus disease.
Andrews, N +16 more
core +1 more source