Results 111 to 120 of about 480,499 (310)

Molecular analysis of an outbreak of lethal postpartum sepsis caused by Streptococcus pyogenes [PDF]

, 2013
This work was supported by the United Kingdom Clinical Research Collaboration, which funds the National Centre for Infection Prevention and Management at Imperial College London.
Holden, M.T., Bentley, S.D., Holden, MTG, Davies, F.J., Sriskandan, S., Dryden, M., Davies, Frances J., Bentley, SD, Lawrenson, RA, Turner, C.E., Farzaneh, L, Sriskandan, S, Efstratiou, A, Holden, Matthew Thomas Geoffrey, Bentley, Stephen D., Dryden, M, Davies, FJ, Efstratiou, A., Farzaneh, Leili, Turner, CE, Lawrenson, Richard A., Efstratiou, Androulla, Lawrenson, R.A., Farzaneh, L., Turner, Claire E., Sriskandan, Shiranee, Dryden, Matthew   +26 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

The effects of probiotics intervention on oral health outcomes: a comprehensive umbrella review of meta-analyses

Frontiers in Oral Health
BackgroundProbiotics are proposed adjuncts for oral health, but findings from meta-analyses are inconsistent. We conducted an umbrella review of meta-analyses to synthesize evidence on probiotics’ effects on cariogenic bacteria such as Streptococus (S ...
Zhen Tang, Yunzhen Deng, Gang Guo, LiLi Zhou   +3 more
doaj   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Detection of streptococcal deoxyribonucleic acid with polymerase chain reaction in excised valvular tissue of rheumatic heart disease patients

Annals of Pediatric Cardiology
Introduction: Rheumatic heart disease (RHD) is traditionally attributed to cumulative valvular injury from the recurrent episodes of acute rheumatic fever.
Nitin Kumar Parashar, Mohsin Raj Mantoo, Sudheer Arava, Sivasubramanian Ramakrishnan, Palleti Rajashekar, Mumun Sinha, Sandeep Seth, Balram Bhargava   +7 more
doaj   +1 more source

Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo [PDF]

, 2012
Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens.
Hermans Peter W. M., Brown, J.S., Durmort Claire, Jeremy S. Brown, Jonathan M Cohen, Emilie Camberlein, Hermans, P.W.M., Camberlein Emilie, Durmort, C, Vernet Thierry, MacDonald, N, Chimalapati, S, Claire Durmort, Jeremy S Brown, Timothy Mitchell, Suneeta Chimalapati, Cohen, J.M., Camberlein, E, Peter W. M. Hermans, Brown, JS, Chimalapati, S., Hermans, PWM, Vernet, T., Chimalapati Suneeta, Camberlein, E., Mitchell, T., Mitchell Timothy, MacDonald, N., Peter W M Hermans, Nathanael MacDonald, Thierry Vernet, Vernet, T, Cohen, JM, Cohen Jonathan M., Brown Jeremy S., MacDonald Nathanael, Durmort, C., Jonathan M. Cohen, Mitchell, T   +38 more
core   +3 more sources

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Clonal analysis and virulence of Australian isolates of Streptococcus suis type 2 [PDF]

, 1994
Multilocus enzyme electrophoresis was used to divide 124 Australian isolates of Streptococcus suis type 2 into 17 electrophoretic types (ETs). Isolates in ET 1 were the most frequent cause of disease amongst Western Australian pigs, but isolates of ET 8 ...
Atyeo, R.F., Lee, B.J., Robertson, I.D., Hampson, D.J., Trott, D.J., Mwaniki, C.G.   +5 more
core  

Characterization of novel beta-galactosidase activity that contributes to glycoprotein degradation and virulence in Streptococcus pneumoniae.

, 2010
The pneumococcus obtains its energy from the metabolism of host glycosides. Therefore, efficient degradation of host glycoproteins is integral to pneumococcal virulence.
Andrew, Peter W, Homer, Karen A, Yesilkaya, Hasan, Terra, Vanessa S, Rao, Susmitha G   +4 more
core   +1 more source