An Uncommon Case of Pyogenic Spondylodiscitis Caused by Gemella morbillorum
An 81-year-old man presented with severe back pain. Magnetic resonance imaging detected L5/S discitis without signs of epidural abscess. Punctures of the disc revealed that the causative organism was Gemella morbillorum (G. morbillorum), which is part of
Yasuhiro Tsuchido +3 more
core +1 more source
Genome characterization and population genetic structure of the zoonotic pathogen, streptococcus canis [PDF]
Background - Streptococcus canis is an important opportunistic pathogen of dogs and cats that can also infect a wide range of additional mammals including cows where it can cause mastitis. It is also an emerging human pathogen.
Zadoks Ruth N +45 more
core +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source
Bacteremia due to Gemella morbillorum
Gemella morbillorum, previously known as Streptococcus morbillorum was reclassified into the genus Gemella in 1988 on the basis of DNA hybridization(1). Human infections caused by G. morbillorum are rare. The cases reported are predominantly endovascular
Chaudhry, Rama +4 more
core +1 more source
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
Aging and periodontitis increase brain dissemination of oral bacteria
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu +7 more
wiley +1 more source
Mapping the subgingival HerBiome and HisBiome over the human healthspan
Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam +3 more
wiley +1 more source
Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis [PDF]
Background Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the gut, genital tract and mammary gland ...
Andy Barron +57 more
core +5 more sources
Genomic Map of Escherichia coli and Single Nucleotide Polymorphism Markers in Colorectal Cancer
This study identified colorectal cancer‐associated SNPs in Escherichia coli using PacBio full‐genome sequencing, establishing a highly accurate SNP‐based model for non‐invasive colorectal cancer risk prediction. ABSTRACT Gut microbial single nucleotide polymorphisms (SNPs) offer stable, specific genetic markers for disease diagnosis.
Yang Xi +10 more
wiley +1 more source
Genomic evidence for the evolution of Streptococcus equi : host restriction, increased virulence, and genetic exchange with human pathogens [PDF]
The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered. Streptococcus equi subspecies equi (S.
Parkhill Julian +117 more
core +1 more source

