Results 41 to 50 of about 122,055 (134)

Parvimonas micra promotes carcinogenesis of colorectal cancer through phenyllactic acid‐induced DNA damage

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Multiomics analysis of the faecal samples from CRC patients found that upregulation of P. micra and PLA was associated with the CRC development. PLA from P. micra via pdhD genes could induce DNA damage via AHR signalling pathway to mediate carcinogenesis.
Shuang Guo, Mujia Cao, Jinjie Wu, Wenhao Ma, Dayi Liang, Hongyu Xie, Yanchun Xie, Zhanhao Luo, Peng Lai, Danling Liu, Wanyi Zeng, Jingbiao Zheng, Mengze Xing, Xiqi Yin, Min Xia, Zhen He   +15 more
wiley   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

Oral Diseases, Volume 32, Issue 5, Page 1237-1272, May 2026.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung, Eirini Militsi, Olivier Huck   +2 more
wiley   +1 more source

Diversity and random forest models of oral microbiomes in periodontal health using publicly available data

Journal of Periodontology, Volume 97, Issue 4, Page 671-684, April 2026.
Abstract Background Evidence on the 16S metabarcoding of supragingival, subgingival, and salivary microbiomes in periodontal health remains limited. We aimed to analyze the diversity and potential of machine‐learning models of supragingival, subgingival, and salivary microbiomes in periodontal health. Methods A total of 848 samples (supragingival = 210;
Alba Regueira‐Iglesias, Berta Suárez‐Rodríguez, Triana Blanco‐Pintos, Alba Sánchez‐Barco, Marta Relvas, Carlos Balsa‐Castro, Inmaculada Tomás   +6 more
wiley   +1 more source

Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis [PDF]

, 2009
Background: Streptococcus suis is a zoonotic pathogen that infects pigs and can occasionally cause serious infections in humans. S. suis infections occur sporadically in human Europe and North America, but a recent major outbreak has been described in ...
Kehoe, M., Gottschalk, M, Mai, Nguyen Thi Hoang, Maskell, Duncan, Dowson, C G, Cherevach, I, Spratt, BG, Quail, M.A., Goodhead, Ian, Xu, J, Slater, J.D., Xu Jianguo, Maskell Duncan J., Nguyen, Tran Chinh, Inna Cherevach, Ian Goodhead, Sanders, M., Dowson, Christopher G., Whatmore Adrian M., Price, Claire, Price, C, Smith, Hilde E., Nicholas J Croucher, Dowson Christopher G., Schultz, C, Price Claire, Cherevach Inna, Neil Chanter, Ward, P N, Rabbinowitsch Ester, Diep, To Song, Ngo, Thi Hoa, Goodhead, I., Croucher, N., Thi Hoang Mai Nguyen, Claire Price, Iversen, P, Whatmore, A M, Jianguo, Xu, To, SD, Parkhill, Julian, Chanter, N, Croucher, NJ, Michael Kehoe, Chinh Nguyen Tran, Ye, Changyun, Tran Bich Chieu, Diep, T S, Holden, M T, Ngo Thi Hoa, Quail, MA, Nguyen, THM, Sanders Mandy, Iversen, P., Tran, BC, Sanders, M, Chinh, Nguyen Tran, Chieu, T B, Bentley, Stephen D., Mai, NTH, Nguyen, TC, Quail, M A, Changyun Ye, Ngo, T H, Holden, M.T.G., Croucher, N J, Whatmore, Adrian M., Hauser, H, Goodhead Ian, Leigh, J.A., Mungall, K, Holden, MTG, Cronin, Ann, Matthew T G Holden, Slater, Josh D., Maskell, Duncan J., Bentley, S., Sharp, S., Rabbinowitsch, E., Parkhill, J., Sharp, S, Mungall, K., To Song Diep, Croucher Nicholas J., Hauser, Heidi, Xu, Jianguo, Iversen Pernille, Smith, H E, Maskell, D.J., Michael A Quail, Stephen Bentley, Smith, HE, Croucher, Nicholas J., Nguyen Thi Hoang Mai, Karen Mungall, Barrell, B.G., Cronin Ann, Slater Josh D., Bentley, S, Smith, H.E., Schultsz, C, Parkhill Julian, Rabbinowitsch, Ester, Rabbinowitsch, E, Kehoe Michael, Hoa Ngo, Thi, Marcelo Gottschalk, Ward, P.N., Leigh James A., Hauser, H., Schultsz, Constance, Hilde E Smith, Philip N Ward, Schultsz, C., Gottschalk Marcelo, Chieu, Tran Bich, Chinh, NT, Adrian M Whatmore, Barrell, B G, Maskell, DJ, Barrell, Barclay G., Josh D Slater, Slater, JD, To, Song Diep, Chieu Tran Bich, Changyun, Ye, Quail, Michael A., Thi Hoa Ngo, Sharp Sarah, Cherevach, I., Spratt, B G, Gottschalk, Marcelo, Julian Parkhill, Spratt Brian G., Barrell, Bart G., Chanter, N., Mai, N T, Diep To Song, Schultsz Constance, Heidi Hauser, Maskell, D J, Ward Philip N., Dowson, CG, Slater, J D, Barrell Barclay G., Leigh, J A, Cherevach, Inna, Bentley, Stephen, Leigh, James A., Ngo, TH, Parkhill, J, Thi, HN, Constance Schultsz, Nguyen Tran Chinh, Holden, Matthew T. G., Iversen, Pernille, Barclay G Barrell, Chieu, TB, Whatmore, AM, Mungall Karen, Ward, Philip N., Cronin, A, Ester Rabbinowitsch, Barrell, BG, Quail Michael A., Sanders, Mandy, Ye Changyun, Goodhead, I, Whatmore, A.M., Ye, C, Bentley Stephen, Brian G Spratt, Chanter Neil, Hauser Heidi, Price, C., Cronin, A., Kehoe, M, Spratt, B.G., Holden Matthew T. G., Smith Hilde E., Duncan J Maskell, Chinh, N T, Sharp, Sarah, Chanter, Neil, Diep, TS, Pernille Iversen, Jianguo Xu, Leigh, JA, Nguyen, Thi Hoang Mai, Gottschalk, M., Mandy Sanders, Spratt, Brian G., James A Leigh, Dowson, C.G., Ward, PN, Christopher G Dowson, Mungall, Karen, Ann Cronin, Kehoe, Michael, Sarah Sharp, Holden, Matthew T. G.; id_orcid   +200 more
core   +1 more source

Streptococcus equi subsp. equi and Streptococcus equi subsp. zooepidemicus [PDF]

, 2013
The bacterium Streptococcus equi subsp. equi (S. equi) is the causative agent of the highly contagious upper respiratory disease "strangles" in horses. The ancestor of S. equi, Streptococcus equi subsp. zooepidemicus (S.
Lindahl, Susanne
core   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, Volume 2, Issue 1, March 2026.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

Identification and characterization of two temperature-induced surface-associated proteins of Streptococcus suis with high homologies to members of the arginine deiminase system of Streptococcus pyogenes [PDF]

, 2002
The present study was performed to identify stress-induced putative virulence proteins of Streptococcus suis. For this, protein expression patterns of streptococci grown at 32, 37, and 42°C were compared by one- and two-dimensional gel electrophoresis ...
Gruening, P., Smith, H.E., Winterhoff, N., Valentin-Weigand, P., Goethe, R., Kalisz, H., Rohde, M.   +6 more
core   +1 more source

Machine learning‐assisted prediction of clinical responses to periodontal treatment

Journal of Periodontology, Volume 96, Issue 11, Page 1199-1212, November 2025.
Abstract Background Periodontitis is among the most prevalent chronic inflammatory conditions globally, and is associated with bone resorption, tooth loss, and systemic complications. While its treatment is largely standardized, individual outcomes vary, with some patients experiencing further disease progression despite adherence. Methods We developed
Balazs Feher, Eduardo H. de Souza Oliveira, Poliana Mendes Duarte, Andreas A. Werdich, William V. Giannobile, Magda Feres   +5 more
wiley   +1 more source

A case of Gemella morbillorum native valve endocarditis and results of in vitro susceptibility testing

, 2021
We present a case of a 48 years old male with Gemella morbillorum native mitral valve endocarditis. Due to poor growth of the organism, antimicrobial susceptibility test (AST) could not be performed using the CLSI approved method.
Joan Pawlak, Louis D. Saravolatz, Farah Tanveer, Dima Youssef   +3 more
core   +1 more source

Microbiological Characteristics of Pathogens Isolated From Blood Cultures of Patients With Acute Cholangitis: Insights From Patients With Biliary‐Enteric Anastomosis

Journal of Hepato-Biliary-Pancreatic Sciences, Volume 32, Issue 10, Page 766-776, October 2025.
Kuhara and colleagues analyzed 366 cases of bacteremic acute cholangitis, focusing on pathogens isolated from blood cultures. Escherichia coli and Klebsiella spp. predominated overall, whereas ESCPM organisms were significantly more frequent in patients with prior biliary‐enteric anastomosis or intervention, highlighting the importance of considering ...
Yuta Kuhara, Hiroki Kitagawa, Yuki Kaiki, Keitaro Omori, Norifumi Shigemoto, Tomoyuki Akita, Kenichiro Uemura, Shingo Fukuma, Shinya Takahashi, Hiroki Ohge   +9 more
wiley   +1 more source