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A plasmid in Streptococcus pneumoniae [PDF]

open access: bronzeJournal of Bacteriology, 1979
Plasmid deoxyribonucleic acid has been detected in three related laboratory strains of Streptococcus pneumoniae. Strains D39S, R36, and R36NC each contain a minimum of two copies per cell of a 2.0-megadalton plasmid (pDP1). A plasmid twice as large as this smaller one is also present in much lower quantity in these strains, but neither plasmid is ...
Michelle Smith, Walter R. Guild
openalex   +4 more sources

Pneumonia and Streptococcus pneumoniae vaccine [PDF]

open access: yesArchives of Pharmacal Research, 2017
Pneumonia is an inflammatory disease of the lung, responsible for high morbidity and mortality worldwide. It is caused by bacteria, viruses, fungi, or other microorganisms. Streptococcus pneumoniae, a gram-positive bacterium with over 90 serotypes, is the most common causative agent.
Gyu-Lee Kim, S. Seon, D. Rhee
semanticscholar   +3 more sources

Macrolide Resistance in Streptococcus pneumoniae [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2016
Streptococcus pneumoniae is a common commensal and an opportunistic pathogen. Suspected pneumococcal upper respiratory infections and pneumonia are often treated with macrolide antibiotics.
Max R. Schroeder, D. S. Stephens
semanticscholar   +4 more sources

Fluoroquinolone-resistant Streptococcus pneumoniae

open access: yesEmerging Infectious Diseases, 2006
To the Editor: In pneumococci, resistance to fluoroquinolones is associated with chromosomal mutations in the quinolone-resistance–determining regions (QRDR) of type II topoisomerase enzymes, predominantly gyrA and parC. Several mutations have been described in these enzymes, but only a few have been shown by in vitro studies to confer resistance: S81F
Mathias W. Pletz   +6 more
doaj   +4 more sources

Telithromycin-resistant Streptococcus pneumoniae

open access: yesEmerging Infectious Diseases, 2005
To the Editor: In recent years, antimicrobial drug resistance in Streptococcus pneumoniae has increased worldwide and is a major health concern. Resistance to β-lactams and macrolides, considered to be first-line therapeutic agents, is particularly high in France and many Asian countries (1–3).
Fred W. Goldstein   +2 more
doaj   +4 more sources

Co-infections and antimicrobial resistance profile of Mycobacterium tuberculosis and Streptococcus pneumoniae among patients with pulmonary infections attending tertiary health facilities in Makurdi, Nigeria [PDF]

open access: yesMicrobes and Infectious Diseases, 2023
Background: Pulmonary infections (Pls) cause mortality in elderly patients that have co-morbidities. These infections are life-threatening in the younger population, especially in infants and children.
Ageje Isaac   +9 more
doaj   +1 more source

Streptococcus pneumoniae

open access: yesJournal of Microbiology, Immunology and Infection, 2015
Research on Streptococcus pneumoniae has revealed key aspects in the study of infectious diseases and pathogen evolution, but pneumococci remain a major cause of morbidity and mortality. New insights into the pathogenic mechanisms of this species confirmed the key role of the capsular polysaccharide but have also identified the important functions ...
Edward N. Janoff, Daniel M. Musher
  +6 more sources

Comparison of Molecular Method and Culture in Detection of Community Acquired Pneumonia in Under Five Year Children in Assam, India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: Pneumonia is the single largest infectious cause of death in children worldwide. Aetiology of pneumonia can be identified using multiple diagnostic tools including culture, serology and Polymerase Chain Reaction (PCR); common pathogens ...
Aparna Sonowal   +4 more
doaj   +1 more source

Lysogeny in Streptococcus pneumoniae [PDF]

open access: yesMicroorganisms, 2020
Bacterial viruses, or bacteriophages, are major contributors to the evolution, pathogenesis and overall biology of their host bacteria. During their life cycle, temperate bacteriophages form stable associations with their host by integrating into the chromosome, a process called lysogeny.
Geneviève Garriss   +3 more
openaire   +4 more sources

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