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A plasmid in Streptococcus pneumoniae [PDF]
Plasmid deoxyribonucleic acid has been detected in three related laboratory strains of Streptococcus pneumoniae. Strains D39S, R36, and R36NC each contain a minimum of two copies per cell of a 2.0-megadalton plasmid (pDP1). A plasmid twice as large as this smaller one is also present in much lower quantity in these strains, but neither plasmid is ...
Michelle Smith, Walter R. Guild
openalex +4 more sources
Pneumonia and Streptococcus pneumoniae vaccine [PDF]
Pneumonia is an inflammatory disease of the lung, responsible for high morbidity and mortality worldwide. It is caused by bacteria, viruses, fungi, or other microorganisms.
Gyu-Lee Kim, S. Seon, D. Rhee
semanticscholar +3 more sources
Macrolide Resistance in Streptococcus pneumoniae [PDF]
Streptococcus pneumoniae is a common commensal and an opportunistic pathogen. Suspected pneumococcal upper respiratory infections and pneumonia are often treated with macrolide antibiotics.
Max R. Schroeder, D. S. Stephens
semanticscholar +5 more sources
The Cell Wall of Streptococcus pneumoniae
Streptococcus pneumoniae has a complex cell wall that plays key roles in cell shape maintenance, growth and cell division, and interactions with components of the human host.
W. Vollmer, O. Massidda, A. Tomasz
semanticscholar +7 more sources
Fluoroquinolone-resistant Streptococcus pneumoniae
To the Editor: In pneumococci, resistance to fluoroquinolones is associated with chromosomal mutations in the quinolone-resistance–determining regions (QRDR) of type II topoisomerase enzymes, predominantly gyrA and parC. Several mutations have been described in these enzymes, but only a few have been shown by in vitro studies to confer resistance: S81F
Mathias W. Pletz+6 more
doaj +4 more sources
Telithromycin-resistant Streptococcus pneumoniae
To the Editor: In recent years, antimicrobial drug resistance in Streptococcus pneumoniae has increased worldwide and is a major health concern. Resistance to β-lactams and macrolides, considered to be first-line therapeutic agents, is particularly high in France and many Asian countries (1–3).
Fred W. Goldstein+2 more
doaj +4 more sources
Co-infections and antimicrobial resistance profile of Mycobacterium tuberculosis and Streptococcus pneumoniae among patients with pulmonary infections attending tertiary health facilities in Makurdi, Nigeria [PDF]
Background: Pulmonary infections (Pls) cause mortality in elderly patients that have co-morbidities. These infections are life-threatening in the younger population, especially in infants and children.
Ageje Isaac+9 more
doaj +1 more source
Lysogeny in Streptococcus pneumoniae [PDF]
Bacterial viruses, or bacteriophages, are major contributors to the evolution, pathogenesis and overall biology of their host bacteria. During their life cycle, temperate bacteriophages form stable associations with their host by integrating into the chromosome, a process called lysogeny.
Geneviève Garriss+3 more
openaire +5 more sources
Research on Streptococcus pneumoniae has revealed key aspects in the study of infectious diseases and pathogen evolution, but pneumococci remain a major cause of morbidity and mortality. New insights into the pathogenic mechanisms of this species confirmed the key role of the capsular polysaccharide but have also identified the important functions ...
Edward N. Janoff, Daniel M. Musher
+6 more sources
Comparison of Molecular Method and Culture in Detection of Community Acquired Pneumonia in Under Five Year Children in Assam, India [PDF]
Introduction: Pneumonia is the single largest infectious cause of death in children worldwide. Aetiology of pneumonia can be identified using multiple diagnostic tools including culture, serology and Polymerase Chain Reaction (PCR); common pathogens ...
Aparna Sonowal+4 more
doaj +1 more source