Results 11 to 20 of about 289,534 (299)
Artificial Intelligence-Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae. [PDF]
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Fitch JS +6 more
europepmc +2 more sources
Pneumonia and Streptococcus pneumoniae vaccine [PDF]
Pneumonia is an inflammatory disease of the lung, responsible for high morbidity and mortality worldwide. It is caused by bacteria, viruses, fungi, or other microorganisms. Streptococcus pneumoniae, a gram-positive bacterium with over 90 serotypes, is the most common causative agent.
Kim, Gyu-Lee +2 more
openaire +2 more sources
Streptococcus pneumoniae [PDF]
El neumococo, Streptococcus pneumoniae, es un microorganismo patógeno capaz de causar en humanos diversas infecciones y procesos invasivos severos. Se trata de una bacteria Gram positiva , que presenta una forma oval y el extremo distal lanceolado. Es inmóvil, no forma endosporas, y es un miembro alfa-hemolítico del género Streptococcus.
Martínez Robleto, María Lisvania +1 more
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Comparison of Molecular Method and Culture in Detection of Community Acquired Pneumonia in Under Five Year Children in Assam, India [PDF]
Introduction: Pneumonia is the single largest infectious cause of death in children worldwide. Aetiology of pneumonia can be identified using multiple diagnostic tools including culture, serology and Polymerase Chain Reaction (PCR); common pathogens ...
Aparna Sonowal +4 more
doaj +1 more source
Lysogeny in Streptococcus pneumoniae [PDF]
Bacterial viruses, or bacteriophages, are major contributors to the evolution, pathogenesis and overall biology of their host bacteria. During their life cycle, temperate bacteriophages form stable associations with their host by integrating into the chromosome, a process called lysogeny.
Geneviève Garriss +1 more
openaire +5 more sources
Rapid and early identification of Streptococcus pneumoniae from positive blood cultures is crucial for the management of patients with bloodstream infections (BSI).
Mohammed Suleiman +6 more
doaj +1 more source
A plasmid in Streptococcus pneumoniae [PDF]
Plasmid deoxyribonucleic acid has been detected in three related laboratory strains of Streptococcus pneumoniae. Strains D39S, R36, and R36NC each contain a minimum of two copies per cell of a 2.0-megadalton plasmid (pDP1). A plasmid twice as large as this smaller one is also present in much lower quantity in these strains, but neither plasmid is ...
M D, Smith, W R, Guild
openaire +2 more sources
Objectives We sought to investigate whether the Dp16 mouse model of Down syndrome (DS) is more susceptible to severe and lethal respiratory tract infection by Streptococcus pneumoniae.
Kelley L. Colvin +5 more
doaj +1 more source
Oropharyngeal Colonization by Streptococcus pneumoniae among Medical Students in Indonesia
Background: Streptococcus pneumoniae may colonize the upper respiratory tract without causing any symptoms. Medical students may be inhabited by these bacteria and transmit them to patients who were prone to infections.
Stella Valencia +2 more
doaj +1 more source
Severe problem of macrolides resistance to common pathogens in China
With the widespread use of macrolide antibiotics in China, common pathogens causing children’s infections, such as Streptococcus pneumoniae, Streptococcus (including Group A streptococcus, Group B streptococcus), Staphylococcus aureus, Bordetella ...
Jialin Li +12 more
doaj +1 more source

