Results 91 to 100 of about 289,534 (299)

High levels of recombination among Streptococcus pneumoniae isolates from the Gambia. [PDF]

, 2011
We carried out multilocus sequence typing (MLST) on 148 pneumococcal carriage isolates collected from children
Bishop, CJ, Donkor, ES, Wren, B, C. J. Bishop, M. Antonio, K. A. Gould, Hanage, WP, W. P. Hanage, Hinds, J, Antonio, M, E. S. Donkor, Gould, KA, J. Hinds, Gould, K, B. Wren   +14 more
core   +1 more source

In‐line Raman spectroscopy real‐time glucose prediction method for commercial pneumococcal vaccine drug substance fermentation manufacturing process control

Biotechnology Progress, EarlyView.
Abstract Traditional off‐line analysis methods to quantify residual metabolite concentrations in a drug substance fermentation process consume valuable time, require costly resources, and demand potentially hazardous manual operations when working with pathogenic biological organisms.
Griffin P. Thomas, Brian C. Marks, Barbara B. Alvarado‐Hernandez, Matthew Woodling, James O'Connor, Roberto Ortiz, John Higgins, Jon Shanter   +7 more
wiley   +1 more source

Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine [PDF]

, 2013
Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children.
Nicholas J Loman, Jacqueline Chan, Tocheva Anna S., O’Connor Leigh, Pallen, Mark J., Constantinidou C., Loman, Nicholas J., Pallen M.J., Faust, Saul N, Faust, Saul N., Loman, Nicholas, Clarke S.C., Tocheva A.S., Constantinidou Chrystala, Mark J Pallen, Loman, Nicholas J, Chan, Jacqueline, Constantinidou, Chrystala, Stuart C Clarke, Pallen, Mark J, Gladstone R.A., O'Connor, Leigh, Chrystala Constantinidou, Clarke, Stuart C, Tocheva, Anna S., Faust, S.N., Clarke, S.C., Johanna M C Jefferies, Loman Nicholas J., Faust Saul N., Clarke Stuart C., Gladstone, Rebecca A., Chan J., O’Connor, Leigh, Leigh O'Connor, Anna S Tocheva, Clarke, Stuart C., Pallen, Mark, Tocheva, Anna S, Jefferies J.M.C., Jefferies, Johanna M C, Loman N.J., Chan Jacqueline, Jefferies, Johanna M.C., Gladstone, Rebecca, Saul N Faust, Jefferies Johanna M. C., Jefferies, Johanna M. C., Faust S.N., Pallen Mark J., Gladstone, Rebecca A, Rebecca A Gladstone, O'Connor L., Gladstone Rebecca A.   +53 more
core   +1 more source

Acción in vitro de diez plantas medicinales sobre diez cepas diferentes de Streptococcus pneumoniae

Anales de la Facultad de Medicina, 2012
Introducción: El portador sano es el principal diseminador de las infecciones neumocócicas por la nasofaringe. Una alternativa para combatirlo son las plantas medicinales.
JM Guevara Duncan, C Fuertes Ruitón, E Valencia Bazalar, JMM Guevara Granados, R Zerpa Larrauri, V Béjar Castillo, L Patiño Gabriel, JC Celis Salinas   +7 more
doaj  

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Intestinal Epithelial Memory: From Inflammatory Imprinting to Metabolite‐Shaped Immune Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Intestinal epithelial cells are rapidly renewing barrier cells that maintain compartmentalization between the luminal environment and the mucosal immune system through epithelial transport, antimicrobial defense, secretory programs, and cytokine‐mediated communication.
Wenjing Yang, Tianming Yu, Yingzi Cong
wiley   +1 more source

The pneumococcal response to oxidative stress includes a role for Rgg. [PDF]

, 2009
Streptococcus pneumoniae resides in the oxygen-rich environment of the upper respiratory tract, and therefore the ability to survive in the presence of oxygen is an important aspect of its in vivo survival. To investigate how S.
Terra, VS, P. W. Andrew, Hasan Yesilkaya (345723), Hinds, Jason, Vanessa S. Terra (3610202), M. E. Bortoni, Andrew, PW, V. S. Terra, Yesilkaya, H, Bortoni, Magda E, Andrew, Peter W, Bortoni, ME, Hinds, J, Peter W. Andrew (153608), Yesilkaya, Hasan, H. Yesilkaya, J. Hinds, Terra, Vanessa S, J. Hinds (7607714)   +18 more
core   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection [PDF]

, 2013
Streptococcus pneumoniae of serotype 3 possess a mucoid capsule and cause disease associated with high mortality rates relative to other pneumococci. Phylogenetic analysis of a complete reference genome and 81 draft sequences from clonal complex 180, the
Mitchell, Tim J, Mitchell, T.J., Hinds, Jason, Susannah J Salter, Janina Dordel (250569), Jason Hinds (41307), Gould, Katherine A, Janina Dordel, Mitchell, AM, Inverarity, D., Birgitta Henriques-Normark (336864), Fookes, Maria C., Julian Parkhill (30393), Harris, Simon R, Fookes, MC, Maria C. Fookes (261889), Salter, SJ, Normark, S., Sarah Browall (469315), Dordel, Janina, Hinds, J, Jason Hinds, Nicholas J Croucher, Zemlickova, Helena, Salter, Susannah J, Barquist, L, Mitchell, Tim J., Inverarity, Donald, Barquist, L., Mitchell, TJ, Staffan Normark, Stephen D Bentley, Katherine A. Gould (469313), Birgitta Henriques-Normark, Andrea M. Mitchell (150475), Gould, KA, Zemlickova, H, Harris, S.R., Susannah J. Salter (466583), Helena Zemlickova (5494223), Julian Parkhill, Maria C Fookes, Fookes, Maria C, Barquist, Lars, Donald Inverarity (469314), Parkhill, Julian, Croucher, NJ, Simon R Harris, Feltwell, Theresa, Croucher, N.J., Simon R. Harris (124597), Henriques-Normark, Birgitta, Gould, Katherine A., Croucher, Nicholas J, Parkhill, J, Harris, Simon R., Theresa Feltwell, Bentley, Stephen D, Lars Barquist (158426), Bentley, Stephen D., Tim J. Mitchell (179143), Gould, K.A., Henriques-Normark, B., Henriques-Normark, B, Feltwell, T, Harris, SR, Theresa Feltwell (66997), Salter, Susannah J., Sarah Browall, Zemlickova, H., Normark, Staffan, Inverarity, D, Bentley, S.D., Hinds, J., Katherine A Gould, Mitchell, Andrea M; id_orcid, Lars Barquist, Mitchell, Andrea M., Bentley, SD, Browall, S, Stephen D. Bentley (137281), Parkhill, J., Donald Inverarity, Staffan Normark (33838), Feltwell, T., Fookes, M.C., Dordel, J., Tim J Mitchell, Mitchell, A.M., Nicholas J. Croucher (158423), Andrea M Mitchell, Browall, S., Dordel, J, Salter, S.J., Browall, Sarah, Normark, S, Helena Zemlickova   +96 more
core   +2 more sources