Results 111 to 120 of about 137,892 (306)

C-reactive protein is essential for innate resistance to pneumococcal infection. [PDF]

, 2014
No deficiency of human C-reactive protein (CRP), or even structural polymorphism of the protein, has yet been reported so its physiological role is not known.
Lawrence, Rachel A., Read, Kevin D., Aviva Petrie, Pepys, M B, Pepys, MB, Hutchinson, Winston L., LSHTM, Read, Kevin D, Raynes, JG, Read, KD, J. Brian Souza, Tennent, G A, Stephan Ellmerich, Loeffler, JM, Simons, JP, Rachel A. Lawrence, Simons, J Paul, Tennent, GA, John G. Raynes, Dundee, Glenys A. Tennent, Ellmerich, Stephan, Ellmerich, S, Tennent, Glenys A, Al-Shawi, Raya, Petrie, A, Tennent, Glenys A., Simons, J. Paul, Lawrence, R A, Jutta M. Loeffler, Lawrence, RA, Hutchinson, Winston L, J. Paul Simons, de Souza, J Brian, de Souza, J. Brian, Kevin D. Read, Raynes, John G., Raynes, J G, Read, K D, Mark B. Pepys, Hutchinson, WL, de Souza, JB, Loeffler, Jutta M, Petrie, Aviva, Al-Shawi, R, Pepys, Mark B., Lawrence, Rachel A, Raynes, John G, Loeffler, J M, de Souza, J B, Hutchinson, W L, Pepys, Mark B, Raya Al‐Shawi, Winston L. Hutchinson, Loeffler, Jutta M., Simons, J P, UCL   +56 more
core   +1 more source

Host Phylogeny and Feeding Habit Jointly Govern Mammalian Gut Microbiota Composition

Integrative Zoology, EarlyView.
Herbivores showed higher alpha diversity than carnivores/omnivores, while omnivores had the highest beta diversity. Host phylogeny influenced gut microbiota more strongly in herbivores/omnivores, with phylogenetic distance correlating to microbiota dissimilarity.
Chaoyuan Cheng, Hongjuan Zhai, Jiajia Feng, Zhibin Zhang   +3 more
wiley   +1 more source

Molecular modelling of the Streptococcus pneumoniae serogroup 6 capsular polysaccharide antigens [PDF]

, 2013
In this thesis, a systematic study of the structural characterization of the capsular polysaccharides of Streptococcus pneumoniae is conducted using Molecular Modelling methods.
Mathai, Neann Sarah, Mathai, Neann
core  

Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]

, 2011
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Mitchell, Tim J, Mitchell, T.J., Jefferies, J.M.C., Greenhalgh, D., Stuart C. Clarke, David Greenhalgh, Lamb, Karen Elaine, McMenamin, Jim, Robertson, C., Inverarity, D., Greenhalgh, D, Diggle, M, Jim McMenamin, Mathew Diggle, Lamb, K, Clarke, S., Edwards, Giles F S, Jefferies, JMC, Mitchell, T., Lamb, K., Johanna M. C. Jefferies, Clarke, SC, Tim J. Mitchell, Clarke, Stuart C, Clarke, S.C., Edwards, G.F.S., Mitchell, Tim J., Inverarity, D, Diggle, Mathew, Smith, A, Inverarity, Donald, McMenamin, J., Smith, Andrew, Mitchell, TJ, McMenamin, J, Lamb, Karen, Robertson, C, Diggle, M., Greenhalgh, David, Andrew Smith, Donald Inverarity, Edwards, G., Smith, A., Clarke, Stuart C., Jefferies, Johanna M C, Jerreries, J., Chris Robertson, Edwards, Giles F.S., Karen Lamb, Jefferies, Johanna M.C., Robertson, Chris, Giles F. S. Edwards, Edwards, GFS   +52 more
core   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Impact of Gentamicin‐Impregnated Collagen Sponge on the Incidence of Access Related Infections After Full‐Support Microaxial Flow Pump Therapy

Artificial Organs, EarlyView.
Local application of gentamicin for wound closure after full‐support microaxial flow pump therapy. ABSTRACT Background Surgically implanted microaxial flow pumps (mAFP) are increasingly used for cardiogenic shock treatment. Standard mAFP explantation is performed bedside with a shortening of the vascular prosthesis, which may represent a potential ...
Gaik Nersesian, Maximilian Rauch, Daniel Lewin, Leonard Pitts, Julius Kaemmel, Anna Stegmann, Julia Stein, Yuriy Hrytsyna, Felix Schoenrath, Volkmar Falk, Evgenij Potapov, Pia Lanmueller   +11 more
wiley   +1 more source

The enzymology of Streptococcus pneumoniae peptidoglycan polymerisation [PDF]

Bacterial cell survival depends on intact peptidoglycan, an extensive cell wall polymer of alternating N-acetylglucosamine and N-acetylmuramic acid residues, cross-linked by short peptides.
Abrahams, Katherine A.
core  

Pyruvate formate lyase is required for pneumococcal fermentative metabolism and virulence.

, 2009
Knowledge of the in vivo physiology and metabolism of Streptococcus pneumoniae is limited, even though pneumococci rely on efficient acquisition and metabolism of the host nutrients for growth and survival.
Andrew, Peter W., Homer, Karen A, Spissu, Francesca, Homer, Karen A., Benisty, Rachel, Porat, Nurith, Neves, Ana R., Andrew, Peter W, Yesilkaya, Hasan, Neves, Ana R, Terra, Vanessa S., Carvalho, Sandra M, Terra, Vanessa S, Carvalho, Sandra M.   +13 more
core   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

TroA of Streptococcus suis is required for manganese acquisition and full virulence

, 2011
Streptococcus suis causes infections in pigs and occasionally in humans resulting in 23 manifestations as meningitis, sepsis, arthritis and septic shock. For survival within the 24 host, S. suis requires numerous nutrients including trace metals.
Smith, H.E., Rebel, M.J., Wichers Schreur, P.J., Rebel, J.M.J., van Putten, J.P.M., Jos P. M. van Putten, Johanna M. J. Rebel, Mari A. Smits, Paul J. Wichgers Schreur, Smits, M.A., Hilde E. Smith, Wichgers Schreur, P.J., Putten, J.P.M., van   +12 more
core   +1 more source