Results 121 to 130 of about 137,892 (306)
A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz +17 more
wiley +1 more source
Background: Pneumonia remain an important public health problem. The primary objective was to determine the proportion of community-acquired pneumonia that is attributable to Streptococcus pneumoniae infection; secondary objectives were the description ...
Marta Di Pasquale +6 more
doaj +1 more source
Introduction Antimicrobial resistance (AMR) may lead to increasing inefficacy and treatment failure of bacterial infections in the future. Antimicrobial stewardship (AMS) programmes are critical to ensuring the continued efficacy of available antimicrobials.
JKH Hoong, C Boyd, C Secombe, D Byrne
wiley +1 more source
Background and Objectives: Streptococcus pneumoniae is the most common cause of invasive infections among both young children and elderly people. Common serotypes causing invasive diseases and the emergence of carriers of Streptococcus pneumoniae in Iran
Seyed-Fazlollah Mousavi +6 more
doaj
Continued control of pneumococcal disease in the UK - the impact of vaccination
Streptococcus pneumoniae, also known as the pneumococcus, is an important cause of morbidity and mortality in the developed and developing world. Pneumococcal conjugate vaccines were first introduced for routine use in the USA in 2000, although the seven-
Gladstone, R.A. +11 more
core +1 more source
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen +7 more
wiley +1 more source
Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage
Clerocidin (CL), a microbial diterpenoid, reacts with DNA via its epoxide group and stimulates DNA cleavage by type II DNA topoisomerases. The molecular basis of CL action is poorly understood.
Fisher, LM +7 more
core +1 more source
Abstract Background Staphylococcus lugdunensis is a coagulase‐negative Staphylococcus that has been increasingly recognised as a significant pathogen capable of causing invasive infections similar to Staphylococcus aureus. Data comparing the clinical manifestations and outcomes of S. lugdunensis bacteraemia to S. aureus bacteraemia remain limited. This
Gemma Webb +5 more
wiley +1 more source
Susceptibilidad a antimicrobianos de patógenos respiratorios en niños provenientes de la comunidad
Objetivo: Determinar la resistencia de los patógenos respiratorios a diferentes antimicrobianos. Material y Métodos: Entre abril y noviembre de 2002 se estudió 177 pacientes que asistieron al consultorio externo de otorrinolaringología del Hospital ...
José M Guevara +5 more
doaj
Structural studies on the sialidases from Streptococcus pneumoniae and Pseudomonas aeruginosa
The sialidases are a group of glycosyl hydrolases that specifically remove terminal sialic acid (Neu5Ac) residues from various glycans. In the two common human pathogenic bacteria Streptococcus pneumoniae and Pseudomonas aeruginosa, these enzymes have
Xu, Guogang
core

