Results 181 to 190 of about 221,945 (286)

High BMI and low cardiorespiratory fitness in adolescence are associated with increased risk of severe bacterial infections in adulthood

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 158-171, January 2026.
Abstract Background Obesity and poor physical fitness in youth are established risk factors for future cardiovascular disease and cancer. However, their potential impact on the risk of severe bacterial infections later in life remains unclear. Methods This register‐based cohort study followed almost 1 million Swedish conscripts (mean age 18.3 years ...
Birger Sourander   +8 more
wiley   +1 more source

Antibacterial and Osteogenic Applications of Ti‐Cu Alloys: A Review of Current Research and Future Directions

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 23, December 8, 2025.
Given the growing interest in antibiotic‐free implant strategies and the need for biocompatible solutions to combat peri‐implantitis and implant failure, this review gives a timely and comprehensive overview of Ti‐Cu alloys as next‐generation biomaterials.
Brandon Fields   +8 more
wiley   +1 more source

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng   +22 more
wiley   +1 more source

Identification of a Pair of Linear or Cyclic Naturally Inspired Bifunctional Lipopeptide Antibiotics That Overcome Antimicrobial Resistance

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
The underexplored bacterial genus Aquimarina harbors a large biosynthetic potential for discovering new antibiotics. Here, the authors identify a pair of linear or cyclic bifunctional cationic lipopeptide antibiotics, aquicidine L and C4, inspired by the aquicidine gene cluster from Aquimarina.
Lei Li, Yiwen Zhou, Yuzhu Wu
wiley   +1 more source

Phenylboronic Acid‐Modified Copper Nanozymes as Nanoscavengers of Bacterial Polysaccharides Causing Acute Lung Injury

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
A novel copper nanocluster coated with 4‐mercaptobenzeneboronic acid (CuMPBA) is developed to target bacterial polysaccharides for addressing complicated acute lung injury (ALI) caused by severe burns and early pulmonary infections. CuMPBA exhibits dual anti‐inflammatory and antibacterial mechanisms by: (a) binding and degrading toxic bacterial ...
Haojie Ge   +4 more
wiley   +1 more source

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