Genotyping Streptococcus Pneumoniae [PDF]
Streptococcus pneumoniae is a potentially deadly human pathogen associated with high morbidity, mortality and global economic burden. The universally used bacterial genotyping methods are multilocus sequence typing and pulsed field gel electrophoresis.
Rayner, Rachael+3 more
openaire +4 more sources
The pneumococcal response to oxidative stress includes a role for Rgg [PDF]
Streptococcus pneumoniae resides in the oxygen-rich environment of the upper respiratory tract, and therefore the ability to survive in the presence of oxygen is an important aspect of its in vivo survival. To investigate how S.
Andrew, PW+4 more
core +3 more sources
Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of Streptococcus pneumoniae Associated with Distinct Alleles of the Type I Restriction-Modification System. [PDF]
The capsule is the dominant Streptococcus pneumoniae virulence factor, yet how variation in capsule thickness is regulated is poorly understood. Here, we describe an unexpected relationship between mutation of adcAII, which encodes a zinc uptake ...
Arioli+51 more
core +3 more sources
Streptococcus pneumoniae Capsular Polysaccharide
The polysaccharide capsule of Streptococcus pneumoniae is the dominant surface structure of the organism and plays a critical role in virulence, principally by interfering with host opsonophagocytic clearance mechanisms.
J. Paton, Claudia Trappetti
semanticscholar +1 more source
Streptococcus pneumoniae: Invasion and Inflammation
Streptococcus pneumoniae (the pneumoccus) is the leading cause of otitis media, community-acquired pneumonia, and bacterial meningitis. The success of the pneumococcus stems from its ability to persist in the population as a commensal and avoid killing ...
A. Loughran, C. Orihuela, E. Tuomanen
semanticscholar +1 more source
Streptococcus pneumoniae’s Virulence and Host Immunity: Aging, Diagnostics, and Prevention
Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases. This pathogen colonizes the nasopharynx of its host asymptomatically, but overtime
Lavida R. K. Brooks, G. Mias
semanticscholar +1 more source
Challenges in estimating the impact of pneumococcal conjugate vaccines through surveillance [PDF]
SCOPUS: re.jinfo:eu-repo/semantics ...
Hanquet, Germaine, Vergison, Anne
core +1 more source
Optimization of Loop-Mediated Isothermal Amplification Reaction for Detecting Streptococcus pneumoniae Serotypes in Clinical Nasopharynx Swab Samples [PDF]
Current molecular PCR-based methods for identifying Streptococcus pneumoniae, the primary cause of pneumonia, meningitis, and other invasive diseases, are accurate but require expensive infrastructure and have a long run time, which restricts their use ...
Mozef Tjandrawati+4 more
doaj +1 more source
Mechanisms of Naturally Acquired Immunity to Streptococcus pneumoniae
In this review we give an update on the mechanisms of naturally acquired immunity against Streptococcus pneumoniae, one of the major human bacterial pathogens that is a common cause of pneumonia, septicaemia, and meningitis.
E. Ramos-Sevillano+2 more
semanticscholar +1 more source
Competence in Streptococcus pneumoniae and Close Commensal Relatives: Mechanisms and Implications
The mitis group of streptococci comprises species that are common colonizers of the naso-oral-pharyngeal tract of humans. Streptococcus pneumoniae and Streptococcus mitis are close relatives and share ~60–80% of orthologous genes, but still present ...
G. Salvadori+3 more
semanticscholar +1 more source