Results 51 to 60 of about 184,405 (335)

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

Angewandte Chemie, EarlyView.
Gromomycins represent a novel class of pentacyclic triterpene antibiotics with a unique biosynthetic pathway independent of the squalene route. These compounds exhibit potent activity against drug‐resistant Gram‐positive pathogens, including MRSA, and their unprecedented cyclization mechanism provides new insight into bacterial triterpene biosynthesis.
Stepan Tistechok, Dmytro Bratiichuk, Hilda Sucipto, Nils Gummerlich, Marc Stierhof, Oleksandr Gromyko, Franziska Fries, Victor Fedorenko, Rolf Müller, Josef Zapp, Maksym Myronovskyi, Andriy Luzhetskyy   +11 more
wiley   +2 more sources

Global and local epidemiology of Group A Streptococcus indicates that naturally-acquired immunity is enduring and strain-specific [PDF]

arXiv, 2021
The bacterium Group A Streptococcus (Streptococcus pyogenes, GAS) is a human-specific pathogen and a major cause of global morbidity and mortality. Despite decades of research our knowledge of GAS infection and immunity is incomplete, hampering vaccine design and other efforts to reduce disease prevalence.
arxiv  

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection [PDF]

, 2013
Streptococcus pneumoniae of serotype 3 possess a mucoid capsule and cause disease associated with high mortality rates relative to other pneumococci. Phylogenetic analysis of a complete reference genome and 81 draft sequences from clonal complex 180, the
Barquist, L, Bentley, SD, Browall, S, Croucher, NJ, Dordel, J, Feltwell, T, Fookes, MC, Gould, KA, Harris, SR, Henriques-Normark, B, Hinds, J, Inverarity, D, Mitchell, AM, Mitchell, TJ, Normark, S, Parkhill, J, Salter, SJ, Zemlickova, H   +17 more
core   +4 more sources

Oral flora of domestic cats in Hong Kong: Identification of antibiotic‐resistant strains

Veterinary Medicine and Science, Volume 9, Issue 1, Page 25-36, January 2023., 2023
Abstract Background As the clinical outcome of bite‐associated infection is related to the oral commensals, evaluating their composition and antibiotic susceptibility pattern can provide more information for the antibiotic treatment of wound infections and increase the awareness of the multidrug‐resistant bacteria in cat oral flora. Aims This study was
Ka Tik Cheung, Hau Yan Chan
wiley   +1 more source

High Prevalence of Asymptomatic Nasopharyngeal Carriage Rate and Multidrug Resistance Pattern of Streptococcus pneumoniae Among Pre-School Children in North Showa Ethiopia

Infection and Drug Resistance, 2022
Mihret Tilahun,1 Mesfin Fiseha,1 Endris Ebrahim,1 Seada Ali,1 Melaku Ashagrie Belete,1 Abdurahaman Seid,1 Wondmagegn Demsiss,1 Alemu Gedefie,1 Selamyhun Tadesse,2 Chernet Belayhun3 1Department of Medical Laboratory Science, College of Medicine and Health
Tilahun M, Fiseha M, Ebrahim E, Ali S, Belete MA, Seid A, Demsiss W, Gedefie A, Tadesse S, Belayhun C   +9 more
doaj  

Rational Antibacterial Therapy of Respiratory Diseases in children

Zdorovʹe Rebenka, 2013
This article presents the results of bacteriological monitoring of 563 children from Zaporizhzhya and Zaporizhzhya region suffering from acute respiratory infections (ARI). 15.3 % cases ARI was caused by Streptococcus pneumoniae pathogen. The analysis of
G.A. Lezhenko, O.Ye. Pashkova, L.I. Pantyushenko   +2 more
doaj   +1 more source

Predicting β-lactam susceptibility from the genome of Streptococcus pneumoniae and other mitis group streptococci

Frontiers in Microbiology, 2023
IntroductionFor Streptococcus pneumoniae, β-lactam susceptibility can be predicted from the amino acid sequence of the penicillin-binding proteins PBP1a, PBP2b, and PBP2x.
Helle Brander Eriksen, Kurt Fuursted, Anders Jensen, Christian Salgård Jensen, Xiaohui Nielsen, Xiaohui Nielsen, Jens Jørgen Christensen, Jens Jørgen Christensen, Patricia Shewmaker, Ana Rita Rebelo, Frank Møller Aarestrup, Kristian Schønning, Hans-Christian Slotved, the One Day in Denmark (ODiD) Consortium   +13 more
doaj   +1 more source

Deep Pneumonia: Attention-Based Contrastive Learning for Class-Imbalanced Pneumonia Lesion Recognition in Chest X-rays [PDF]

arXiv, 2022
Computer-aided X-ray pneumonia lesion recognition is important for accurate diagnosis of pneumonia. With the emergence of deep learning, the identification accuracy of pneumonia has been greatly improved, but there are still some challenges due to the fuzzy appearance of chest X-rays.
arxiv  

Puerperal Streptococcus pneumoniae endometritis : a case report and literature review [PDF]

, 2014
Streptococcus pneumoniae endometritis is an exceedingly rare clinical occurrence in the immunocompetent individual. This case report describes such an occurrence in an otherwise healthy woman 39 days post-normal vaginal delivery. The patient responded to
Abela, Rodianne, Brincat, Mark P., Cuschieri, Paul, Deguara, Catriona, Galea, Gabriel   +4 more
core  

Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]

, 2020
We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM, Hinds, J, Hossain, I, Hua, Y, Mackenzie, GA, Manna, S, Mulholland, EK, Ndiaye, M, Ortika, BD, Salaudeen, R, Satzke, C   +10 more
core   +3 more sources