Results 51 to 60 of about 221,945 (286)

Predicting β-lactam susceptibility from the genome of Streptococcus pneumoniae and other mitis group streptococci

open access: yesFrontiers in Microbiology, 2023
IntroductionFor Streptococcus pneumoniae, β-lactam susceptibility can be predicted from the amino acid sequence of the penicillin-binding proteins PBP1a, PBP2b, and PBP2x.
Helle Brander Eriksen   +13 more
doaj   +1 more source

In Vitro Antimicrobial Activities of Organic Acids and Their Derivatives on Several Species of Gram-Negative and Gram-Positive Bacteria. [PDF]

open access: yes, 2019
The objective of this study was to determine the in vitro antimicrobial activity of several organic acids and their derivatives against Gram-positive (G+) and Gram-negative (G-) bacteria.
Atwill, Edward Robert   +8 more
core   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

Rational Antibacterial Therapy of Respiratory Diseases in children

open access: yesZdorovʹe Rebenka, 2013
This article presents the results of bacteriological monitoring of 563 children from Zaporizhzhya and Zaporizhzhya region suffering from acute respiratory infections (ARI). 15.3 % cases ARI was caused by Streptococcus pneumoniae pathogen. The analysis of
G.A. Lezhenko   +2 more
doaj   +1 more source

Risk factors of mortality for children with Streptococcus pneumoniae meningitis

open access: yesZhongguo linchuang yanjiu, 2023
Objective To explore the risk factors of mortality for children with Streptococcus pneumococcal meningitis. Methods A retrospective analysis was conducted on the clinical data of 41 hospitalized children diagnosed as Streptococcus pneumoniae menigitis ...
CAI Sha, ZHU Chun-hui, DAI Shu-ming, GAO Mei-ling, HU Yun
doaj   +1 more source

ApuA, a multifunctional x-glucan-degrading enzyme of Streptococcus suis, mediates adhesion to porcine epithelium and mucus [PDF]

open access: yes, 2010
We have identified apuA in Streptococcus suis, which encodes a bifunctional amylopullulanase with conserved -amylase and pullulanase substrate-binding domains and catalytic motifs.
Ferrando, M.L.   +4 more
core   +2 more sources

PCR for the detection of pathogens in neonatal early onset sepsis. [PDF]

open access: yes, 2020
BACKGROUND: A large proportion of neonates are treated for presumed bacterial sepsis with broad spectrum antibiotics even though their blood cultures subsequently show no growth. This study aimed to investigate PCR-based methods to identify pathogens not
Bedford Russell, A   +8 more
core   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

open access: yesAdvanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin   +3 more
wiley   +1 more source

Serotypes and antimicrobial resistance of meningeal isolates of Streptococcus pneumonia. Cuba, 2007-2012

open access: yesVacciMonitor, 2014
An observational study was conducted to know the serotypes and antimicrobial susceptibility of isolates of Streptococcus pneumoniae responsible for meningitis in Cuba, where there is no vaccine yet to prevent invasive pneumococcal disease.
Gilda Toraño-Peraza   +5 more
doaj  

Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent pneumococcal conjugate vaccine. [PDF]

open access: yes, 2008
BACKGROUND: The study describes the molecular epidemiology of Streptococcus pneumoniae causing invasive disease in Gambian children METHODS: One hundred and thirty-two S. pneumoniae isolates were recovered from children aged 2-29 months during the course
Adegbola, Richard A   +14 more
core   +2 more sources

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