Antibiotic susceptibility of Streptococcus species that cause pharyngitis in children
Background: Group A Streptococcus (GAS) significantly impacts global health, especially among children aged 5–14 years, causing approximately 288 million episodes of sore throat annually and resulting in around 100,000 disability-adjusted life years ...
Ruqaya Ammar Ammin ,+4 more
doaj +1 more source
Thermoregulation of Capsule Production by Streptococcus pyogenes
The capsule of Streptococcus pyogenes serves as an adhesin as well as an anti-phagocytic factor by binding to CD44 on keratinocytes of the pharyngeal mucosa and the skin, the main entry sites of the pathogen. We discovered that S. pyogenes HSC5 and MGAS315 strains are further thermoregulated for capsule production at a post-transcriptional level in ...
Bernard Beall+5 more
openaire +5 more sources
Prime Editing: A Revolutionary Technology for Precise Treatment of Genetic Disorders
This review outlines the latest research advancements in prime editing technology, delivery strategies, and the challenges that must be addressed to fully realize its therapeutic potential, emphasizing the high potential of prime editing in the remission or cure of genetic diseases. ABSTRACT Genetic diseases have long posed significant challenges, with
Mengyao Li, Yi Lin, Qiang Cheng, Tuo Wei
wiley +1 more source
Group a streptococcal serotypes isolated from healthy schoolchildren in iran [PDF]
Serotypes of group A streptococci are still a major cause of pharyngitis and some post-infectious sequelae such as rheumatic fever. As part of the worldwide effort to clarify the epidemiological pattern of group A streptococci in different countries, the
Fazeli, M.R.+6 more
core
Respiratory admissions and impact of COVID‐19 lockdowns for children with severe cerebral palsy
In a population cohort of children with severe cerebral palsy, there was a reduced frequency of hospitalization for respiratory illness during periods of restricted social contact, implemented to reduce transmission of COVID‐19. This mirrored trends in the wider population and underlines the importance of community viral transmission in these children.
Susan M. Reid+9 more
wiley +1 more source
Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae [PDF]
The physiological functions of the acute phase protein serum amyloid P (SAP) component are not well defined, although they are likely to be important, as no natural state of SAP deficiency has been reported.
Botto, M.+3 more
core
En función de la CMB del aceite esencial de ishpingo (0.26%) y del aceite esencial de clavo de olor (1.56%) frente a Streptococcus mutans y Streptococcus pyogenes, determinada mediante el método de dilución en medio líquido, se elaboró un colutorio.
Tatiana de los Ángeles Mosquera+1 more
doaj +1 more source
Streptococcus pyogenes Escapes from Autophagy [PDF]
Autophagy is important for innate defense against intracellular bacteria, such as Group A Streptococcus (GAS). In this issue of Cell Host & Microbe, Barnett et al. (2013) demonstrate that the globally disseminated serotype M1T1 clone of GAS can evade autophagy via streptococcal cysteine protease SpeB-mediated degradation of ubiquitin-LC3 adaptor ...
openaire +3 more sources
The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
Disturbances of the microbiota–gut–brain axis are evident in people with Huntington's disease (HD) and in HD animal models. Here, we provide an overview of how the trillions of microorganisms residing in the gut, their secretory products, and the microbiota–gut–brain axis may contribute to HD pathogenesis.
Millicent N. Ekwudo+2 more
wiley +1 more source
Bacteriological examination of the udder samples collected from sheep and goats slaughtered at a local abattoir in elazığ [PDF]
In this study. 133 udder lobes from 89 mastitic sheep and 67 from 40 mastitic goats slaughtered at a local abattoir in Elazığ, were collected for bacteriological examination.
H. Basri Gülcü, Hasan Öngör
doaj