Results 191 to 200 of about 253,897 (321)

Missed Opportunities for Preventing or Diagnosing Acute Rheumatic Fever: A Retrospective Cohort Study of 20 Young Australians Diagnosed With Rheumatic Heart Disease on Screening Echocardiography

open access: yesJournal of Paediatrics and Child Health, Volume 61, Issue 5, Page 741-746, May 2025.
ABSTRACT Background and Aim A cross‐sectional echocardiographic screening study in a remote Aboriginal community in Australia identified hyperendemic levels of rheumatic heart disease (RHD). 20/613 screened were newly diagnosed with RHD, and 18/20 had no known history of acute rheumatic fever (ARF). Our aim was to explore the medical histories of those
Oliver Rouhiainen   +8 more
wiley   +1 more source

Multiple independent MGR5 alleles contribute to a clinal pattern in leaf magnesium across the distribution of Arabidopsis thaliana

open access: yesNew Phytologist, Volume 246, Issue 4, Page 1861-1874, May 2025.
Summary Magnesium (Mg) is a crucial element in plants, particularly for photosynthesis. Mg homeostasis is influenced by environmental and genetic factors, and our understanding of its variation in natural populations remains incomplete. We examine the variation in leaf Mg accumulation across the distribution of Arabidopsis thaliana, and we investigate ...
Emmanuel Tergemina   +3 more
wiley   +1 more source

Novel in vivo models of autosomal optic atrophy reveal conserved pathological changes in neuronal mitochondrial structure and function

open access: yesThe FASEB Journal, Volume 39, Issue 7, 15 April 2025.
Autosomal optic atrophy (AOA) is a hereditary condition caused by mutations in OPA1, leading to retinal ganglion cell (RGC) degeneration. This study introduces two novel models to study OPA1 loss in neurons, revealing reduced life span and impaired visual function.
Elin L. Strachan   +9 more
wiley   +1 more source

Advances and Challenges in the Development of Immobilized Enzymes for Batch and Flow Biocatalyzed Processes

open access: yesChemSusChem, Volume 18, Issue 8, April 14, 2025.
Recent advancements in the preparation of immobilized enzymes have improved both batch and continuous flow biocatalytic processes, essential for cost‐effective, sustainable production in the fine chemicals and pharmaceutical industries. This review examines advancements in carrier‐free methods, entrapment strategies, and support‐based approaches ...
Stefania Patti   +5 more
wiley   +1 more source

Is There Emergence of β-Lactam Antibiotic-Resistant Streptococcus pyogenes in China?

open access: yesInfection and Drug Resistance, 2020
Dingle Yu,1,2,* Yuejie Zheng,2,* Yonghong Yang1,2 1Laboratory of Microbiology and Immunology, Beijing Children’s Hospital Affiliated to Capital Medical University, Beijing, People’s Republic of China; 2Department of Respiratory, Shenzhen ...
Yu D, Zheng Y, Yang Y
doaj  

A Surrogate Endpoint Based Provisional Approval Causal Roadmap [PDF]

open access: yesarXiv
For many rare diseases with no approved preventive interventions, promising interventions exist, yet it has been difficult to conduct a pivotal phase 3 trial that could provide direct evidence demonstrating a beneficial effect on the target disease outcome.
arxiv  

PURIFICATION AND PROPERTIES OFN-ACETYL-d-GLUCOSAMINE KINASE FROMSTREPTOCOCCUS PYOGENES [PDF]

open access: bronze, 1964
L. D. Zeleznick   +4 more
openalex   +1 more source

High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population

open access: yesNature Network Boston, 2018
D. Wagner   +7 more
semanticscholar   +1 more source

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