Results 171 to 180 of about 55,479 (273)

Advancing Antiviral Design: Integrating Natural Products, Computation and Targeted Delivery

open access: yesChemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
A stepwise translational framework linking natural‐product discovery, computational prioritisation, experimental validation, lead optimisation and targeted delivery is proposed to advance antiviral design. ABSTRACT The COVID‐19 pandemic highlighted the role of rapid viral mutation and global connectivity in accelerating viral emergence and spread ...
Adedayo Ayodeji Lanrewaju   +3 more
wiley   +1 more source

Methicillin‐resistant Staphylococcus aureus bloodstream infections in the Northern Territory of Australia 2017–2022

open access: yesInternal Medicine Journal, Volume 56, Issue 7, Page 1200-1208, July 2026.
ABSTRACT Background Methicillin‐resistant Staphylococcus aureus (MRSA) bloodstream infections (BSIs) cause significant morbidity and mortality. In Australia's Northern Territory (NT), MRSA BSI prevalence is disproportionately high. Vancomycin remains standard therapy despite toxicity and complex monitoring requirements.
Sara Davison   +7 more
wiley   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 7, Page 1100-1198, July 2026.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev   +5 more
wiley   +1 more source

Prediction of antibiotic target proteins of streptococcus pyogenes using network pharmacology approach

open access: yesSokoto Journal of Medical Laboratory Science
Many extracellular components secreted by Group A Streptococcus, also called S. pyogenes, are believed to be virulence factors. Therefore, this study aimed to predict antibiotic target proteins from S.
Omobhude Fidelis Aluefua*, Abdulmajeed Yunusa, Ridwanu Zauro Abubakar
doaj  

Case Report: Endobronchial antibiotic instillation for refractory lung abscess due to <i>Streptococcus pyogenes</i>. [PDF]

open access: yesFront Med (Lausanne)
Doran JA   +9 more
europepmc   +1 more source

Assessing the Reduction of Recurrent Admissions Using OM‐85 for the Treatment of Preschool Wheeze (ARROW): Protocol for a Multi‐Centre, Randomised, Double‐Blind, Placebo‐Controlled Trial

open access: yesJournal of Paediatrics and Child Health, Volume 62, Issue 7, Page 1244-1254, July 2026.
ABSTRACT Aims Acute wheezing illnesses are among the most common reasons preschool‐aged children are admitted to hospital. Readmission rates are high, and novel preventive strategies are required. OM‐85 is an orally administered bacterial lysate that stimulates anti‐viral immune responses and reduces excessive airway inflammation associated with ...
Jessica C. Costa‐Pinto   +114 more
wiley   +1 more source

Enhanced Rice Yellow Mottle Virus Resistance via CRISPR/Cas9‐Targeted Mutagenesis of the Rice eIF(iso)4G Gene

open access: yesMolecular Plant Pathology, Volume 27, Issue 7, July 2026.
Using CRISPR/Cas9 to edit the susceptibility gene in rice eIF(iso)4G helped to lower the infection of rice yellow mottle virus in mutated lines of the Indica rice cultivar IR2793‐80‐01. ABSTRACT Rice is a staple crop primarily recognised for its high content of carbohydrates and proteins.
Antony Kigaru   +6 more
wiley   +1 more source

Osteoarticular Sporotrichosis in a Brazilian Endemic Setting: Associated Factors and Outcomes

open access: yesMycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Background Osteoarticular infection is an emerging complication of sporotrichosis, often leading to a significant increase in morbidity and longer treatment. Methods We conducted a retrospective cohort study of osteoarticular sporotrichosis (OS) in southeastern Brazil (2014–2024) using clinical, epidemiological, and molecular data.
Vanessa Caroline Randi Magalhães   +14 more
wiley   +1 more source

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