Results 171 to 180 of about 55,479 (273)
Advancing Antiviral Design: Integrating Natural Products, Computation and Targeted Delivery
A stepwise translational framework linking natural‐product discovery, computational prioritisation, experimental validation, lead optimisation and targeted delivery is proposed to advance antiviral design. ABSTRACT The COVID‐19 pandemic highlighted the role of rapid viral mutation and global connectivity in accelerating viral emergence and spread ...
Adedayo Ayodeji Lanrewaju +3 more
wiley +1 more source
ABSTRACT Background Methicillin‐resistant Staphylococcus aureus (MRSA) bloodstream infections (BSIs) cause significant morbidity and mortality. In Australia's Northern Territory (NT), MRSA BSI prevalence is disproportionately high. Vancomycin remains standard therapy despite toxicity and complex monitoring requirements.
Sara Davison +7 more
wiley +1 more source
Carbon metabolism and niche adaptation in <i>Streptococcus pyogenes</i> pathogenesis. [PDF]
Xu W, Okumura CYM.
europepmc +1 more source
Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev +5 more
wiley +1 more source
Many extracellular components secreted by Group A Streptococcus, also called S. pyogenes, are believed to be virulence factors. Therefore, this study aimed to predict antibiotic target proteins from S.
Omobhude Fidelis Aluefua*, Abdulmajeed Yunusa, Ridwanu Zauro Abubakar
doaj
Case Report: Endobronchial antibiotic instillation for refractory lung abscess due to <i>Streptococcus pyogenes</i>. [PDF]
Doran JA +9 more
europepmc +1 more source
ABSTRACT Aims Acute wheezing illnesses are among the most common reasons preschool‐aged children are admitted to hospital. Readmission rates are high, and novel preventive strategies are required. OM‐85 is an orally administered bacterial lysate that stimulates anti‐viral immune responses and reduces excessive airway inflammation associated with ...
Jessica C. Costa‐Pinto +114 more
wiley +1 more source
Streptococcus pyogenes-Induced Necrotizing Pneumonia With Pleural Effusion in a Child: Role of Medical Thoracoscopy. [PDF]
Zhu L +7 more
europepmc +1 more source
Using CRISPR/Cas9 to edit the susceptibility gene in rice eIF(iso)4G helped to lower the infection of rice yellow mottle virus in mutated lines of the Indica rice cultivar IR2793‐80‐01. ABSTRACT Rice is a staple crop primarily recognised for its high content of carbohydrates and proteins.
Antony Kigaru +6 more
wiley +1 more source
Osteoarticular Sporotrichosis in a Brazilian Endemic Setting: Associated Factors and Outcomes
ABSTRACT Background Osteoarticular infection is an emerging complication of sporotrichosis, often leading to a significant increase in morbidity and longer treatment. Methods We conducted a retrospective cohort study of osteoarticular sporotrichosis (OS) in southeastern Brazil (2014–2024) using clinical, epidemiological, and molecular data.
Vanessa Caroline Randi Magalhães +14 more
wiley +1 more source

