Results 181 to 190 of about 14,446 (212)
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Species specificity of streptokinase
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1983Streptokinase, a bacterial protein, forms a complex with human plasminogen which results in a conformational change in the plasminogen molecule and the exposure of an active center. The plasminogen-streptokinase complex is an activator of plasminogen and is rapidly converted to a plasmin-streptokinase complex which, in the human, is also an activator ...
Daniel L. Kline, James A. Marcum
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Streptokinase-Induced Anaphylaxis
DICP, 1989Streptokinase is a thrombolytic agent used most commonly for the dissolution of thrombi obstructing coronary arteries during acute myocardial infarction (MI). Anaphylactic reactions induced by streptokinase occur rarely. We report the case of a patient with acute MI who developed anaphylaxis shortly after the initiation of an intravenous infusion of ...
Matthew Antalek +4 more
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Anaphylactic Reactivity to Streptokinase
JAMA: The Journal of the American Medical Association, 1984Streptokinase is used worldwide as a thrombolytic agent. Allergic reactions have been observed to streptokinase; however, the immunologic mechanisms have not been described. In a case of an anaphylactic reaction to intravenously administered streptokinase during the evolution of a myocardial infarction, the patient had elevated specific IgE and IgG ...
Roy Patterson, Kris G. McGrath
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Streptokinase and Buerger's Disease
Nature, 1963BUERGER originally described thromboangiitis obliterans as primarily a thrombotic process occurring in arteries and veins1 ; later he postulated that the thrombosis arose from an angiitis2. Impressed with the thrombotic aspects of the disease, our laboratory undertook an investigation of clot formation and dissolution in Buerger's disease.
Norman Ende, Norman Ende
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Archives of Internal Medicine, 1986
To the Editor. —We found the recent article by Dykewicz et al 1 most valuable. We have a protocol for use of intravenous streptokinase in our community hospital with which we have treated more than 60 patients since January 1983. To date, we have observed no untoward effects, but we have excluded patients from the protocol who have received ...
Harold G. Morse, Sandra Harley McClellan
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To the Editor. —We found the recent article by Dykewicz et al 1 most valuable. We have a protocol for use of intravenous streptokinase in our community hospital with which we have treated more than 60 patients since January 1983. To date, we have observed no untoward effects, but we have excluded patients from the protocol who have received ...
Harold G. Morse, Sandra Harley McClellan
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1978
As early as 1933, β-hemolytic streptococci were found to secrete into the culture medium a substance able to dissolve fibrin clots (Tillet and Garner, 1933). Since this substance, now known as streptokinase, represented a potential thrombolytic agent, the possibility of its use in human therapy attracted growing interest.
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As early as 1933, β-hemolytic streptococci were found to secrete into the culture medium a substance able to dissolve fibrin clots (Tillet and Garner, 1933). Since this substance, now known as streptokinase, represented a potential thrombolytic agent, the possibility of its use in human therapy attracted growing interest.
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2001
The primary structure of human plasminogen (HPg), diagrammed in Fig. 1, has been deduced from the nucleotide sequence of the cDNA (Forsgren et al. 1987) and genomic DNA (Petersen et al. 1990) that encode this protein, and has been directly determined by amino acid sequence analysis (Wiman 1973; Wiman and Wallen 1975; Wiman 1977; Sottrup-Jensen et al ...
V. A. Ploplis, F. J. Castellino
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The primary structure of human plasminogen (HPg), diagrammed in Fig. 1, has been deduced from the nucleotide sequence of the cDNA (Forsgren et al. 1987) and genomic DNA (Petersen et al. 1990) that encode this protein, and has been directly determined by amino acid sequence analysis (Wiman 1973; Wiman and Wallen 1975; Wiman 1977; Sottrup-Jensen et al ...
V. A. Ploplis, F. J. Castellino
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1978
Streptokinase (SK), an extracellular protein produced by various strains of streptococci, is capable of converting human plasminogen to plasmin. Its capacity to cause lysis of blood clots was first described by Tillet and Garner in 1933. This effect was thought to be due to direct enzymatic action on the fibrin of these clots.
F. B. Taylor, P. C. Comp
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Streptokinase (SK), an extracellular protein produced by various strains of streptococci, is capable of converting human plasminogen to plasmin. Its capacity to cause lysis of blood clots was first described by Tillet and Garner in 1933. This effect was thought to be due to direct enzymatic action on the fibrin of these clots.
F. B. Taylor, P. C. Comp
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THROMBOLYTIC THERAPY WITH STREPTOKINASE
Medical Journal of Australia, 1970Biggs Jc, Chesterman Cn
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