Insights Into the Susceptibility of Fungal Infection and STAT3 Genetic Mutations
ABSTRACT Signal transducer and activator of transcription 3 (STAT3) is a key transcription factor that regulates a spectrum of genes and signalling pathways critical for the antifungal immune response. Mutations in the STAT3 gene confer susceptibility to severe and recurrent fungal infections, predominantly via disruption of interleukin‐17 (IL‐17 ...
Fengming Li +5 more
wiley +1 more source
ABSTRACT Objective To describe the clinical course and outcome of adjuvant topical mitomycin C (MMC) therapy following incomplete resection of a conjunctival amelanotic melanoma in a dog. Animals Studied A 15‐year‐old spayed‐female Shih Tzu presented with a conjunctival mass in the right eye (OD).
Junyeong Ahn +4 more
wiley +1 more source
Crystal Structure and Conformational Dynamics of N─N Bond‐Forming Piperazate Synthase
Piperazate synthases (PZSs) catalyze the key N─N bond formation in the biosynthesis of the rare amino acid piperazic acid. X‐ray crystal structures of apo‐ and holo‐SbPZS show a dimeric enzyme with two heme‐containing active sites, where histidine residues coordinate the iron centers.
Nikita Pal +7 more
wiley +1 more source
In this study, three Streptomyces strains (DSM 41013, DSM 41029, and DSM 41036) were subjected to taxogenomic and genome mining for biosynthetic gene clusters (BGCs). The strainshad genome sizes of 8.7, 6.9, and 7.9 Mb, with GC contents of 72, 73.5, and 72%, respectively. Genome-based phylogenetic analysis, including digital DNA-DNA hybridization (dDDH)
Ulrike Tarazona Janampa +3 more
openaire +1 more source
MICROORGANISMOS BENÉFICOS EN EL CONTROL DE ENFERMEDADES EN JENGIBRE
En Peñas Blanca, San Ramón de Alajuela, se evaluó la acción supresora de las cepas de Trichoderma viride 2C-PR, Bacillus subtilis 002R y Streptomyces griseus 001, en el combate de Fusarium solani, Rhizoctonia solani, Pseudomonas sp y Erwinia ...
Marena Chavarría +2 more
doaj
Schematic illustration of the workflow from DNA sequence‐based research to expression in shaking flasks and subsequent purification via IMAC. The obtained enzymes broaden the toolbox of enzymes used for halogenation reactions with differing catalytic properties and tolerances to reaction‐related conditions.
Sonja Schönrock +2 more
wiley +1 more source
<i>Streptomyces</i>: boost chassis strains for production of invaluable natural products. [PDF]
Chen S +5 more
europepmc +1 more source
<i>Streptomyces pallidus</i> sp. nov. and <i>Streptomyces qianjiangensis</i> sp. nov. isolated from the rhizosphere soil of <i>Cyclosorus acuminatus</i>. [PDF]
Mingjun K +9 more
europepmc +1 more source
Genome sequences of five <i>Streptomyces</i> type strains (<i>Streptomyces argenteolus</i>, <i>Streptomyces pratensis</i>, <i>Streptomyces puniceus</i>, <i>Streptomyces spiroverticillatus</i>, and <i>Streptomyces sundarbansensis</i>). [PDF]
Biessy A +5 more
europepmc +1 more source
Genome mining of amylases and amylase inhibitors from <i>Streptomyces</i>. [PDF]
Lawaetz AC, Gannon A, Hoskisson PA.
europepmc +1 more source

