Kinetic model of metabolic network for xiamenmycin biosynthetic optimisation
Xiamenmycins, a series of prenylated benzopyran compounds with anti‐fibrotic bioactivities, were isolated from a mangrove‐derived Streptomyces xiamenensis. To fulfil the requirements of pharmaceutical investigations, a high production of xiamenmycin is needed.
Min‐juan Xu +4 more
wiley +1 more source
From the deep sea-derived Streptomyces xiamenensis MCCC 1A01570, eight cyclic dipeptides (1–8) and five phenolics (9–13) were obtained. Cyclo-(I-Pro-D-Leu) (4) could moderately promote the gene transcriptional function of nuclear receptor RXRα, while 2, 3, and 13 showed weak reduction in RXRα gene transcriptional activities induced by 9-cis-retinoid ...
Wei-Xiang, Lin +7 more
openaire +2 more sources
The aim of this study was to isolate and identify Actinobacteria from Malaysia mangrove forest and screen them for production of antimicrobial secondary metabolites. Eighty‐seven isolates were isolated from soil samples collected at 4 different sites.
Learn-Han Lee +8 more
wiley +1 more source
Modifications of Prenyl Side Chains in Natural Product Biosynthesis
This review summarizes the unique modifications of prenyl side chains involved in natural product biosynthesis, including epoxidation, dehydrogenation, oxidation of methyl groups to carboxyl groups, C−C bond cleavage and oxidative cyclization. Abstract In recent years, there has been a growing interest in understanding the enzymatic machinery ...
Huibin Wang, Yi Yang, Ikuro Abe
wiley +1 more source
Schematic diagrams of metabolic network, heatmaps and box plots summary of the calculated fluxes are shown in the supporting figures.
Zhu, Xiao-Mei +9 more
openaire +1 more source
New Anti-Fibrotic Drug Candidates from Mangrove-Derived Streptomyces xiamenensis Suppressing Local Inflammation and Mechanical Stress in Hypertrophic Scars [PDF]
Xu, Min-Juan +3 more
openaire +2 more sources
A comparative characterization study between fungal and bacterial eumelanin pigments. [PDF]
Bayram S.
europepmc +1 more source
Draft Genome Sequence of Streptomyces sp. Strain G-5, Isolated from Marine Sponge, Kochi Prefecture, Japan. [PDF]
Matsubara Y, Sakurai T, Ulanova D.
europepmc +1 more source
Additive screening and formula optimization of microbial inhibitor having disease prevention and growth promotion effects on Avena sativa. [PDF]
Zhang J, Yao T, Gong W, Gao Y, Zhao G.
europepmc +1 more source
iChip-Inspired Isolation, Bioactivities and Dereplication of Actinomycetota from Portuguese Beach Sediments. [PDF]
Dos Santos JDN +5 more
europepmc +1 more source

