Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang +16 more
wiley +1 more source
Occupational stress, psychological distress, physical symptoms, and their interrelationships among frontline nurses caring for COVID-19 patients in Japan. [PDF]
Nishihara T +4 more
europepmc +1 more source
Influence of Multiple Traumatic Event Types on Mental Health Outcomes: Does Count Matter? [PDF]
The experience of potentially traumatizing events (PTEs) may be associated with conflicting outcomes: individuals may experience greater psychological distress (dose-response theory), or individuals may become more resilient against repeated PTEs (stress-
Brown, Lily A +5 more
core +1 more source
Self-reported Experiences of Students with Autism Spectrum Disorder in Higher Education: A Population-based Sample [PDF]
Postsecondary education functions as the gateway to a host of positive adult outcomes, including financial independence, employment opportunities, and independent living.
Baczewski, Lauren Marie
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Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
The impact of life stress, psychological resources, and proactive behaviors on quality of life among people living with HIV. [PDF]
Nguyen AL +6 more
europepmc +1 more source
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Effects of a yoga-based stress reduction intervention on stress, psychological outcomes and cardiometabolic biomarkers in cancer caregivers: A randomized controlled trial. [PDF]
Lee LJ +9 more
europepmc +1 more source
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo +13 more
wiley +1 more source
Penanganan Stres dan Kesejahteraan Psikologis Pasien Kanker Payudara yang Menjalani Radioterapi di RSUD Dr. Moewardi Surakarta [PDF]
Stress management and psychological well-being in breast cancer patient undergoing radiotherapyBackground: Many breast cancer patients suffer low psychological well-being because the disease and radiotherapy.
Dewi, K. S. (Kartika) +2 more
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