Results 151 to 160 of about 1,792,988 (313)

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

open access: yesAdvanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan   +11 more
wiley   +1 more source

Emotional Effects of the Duration, Efficiency, and Subjective Quality of Sleep in Healthcare Personnel [PDF]

open access: yes, 2019
Considering that both sleep quality and duration are linked to psychological variables, this study analyzed the relationships between sleep components and emotional intelligence and the effects that sleep duration has on stress management and mood in a ...
Barragán Martín, Ana Belén   +4 more
core   +1 more source

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

open access: yesAdvanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini   +8 more
wiley   +1 more source

Causes of Stress and Coping Strategies Adopted by Undergraduate Health Professions Students in a University in the United Arab Emirates

open access: yesSultan Qaboos University Medical Journal, 2013
Objectives: This study aimed to compare causes of stress and coping strategies adopted by a sample of undergraduate health-profession students at the Gulf Medical University, United Arab Emirates.
Kadayam G. Gomathi   +2 more
doaj  

What do sports medicine professionals working in football need to know about sport psychology? [PDF]

open access: yes, 2018
Sport psychology and sports injury are undeniably linked - psychological factors have been shown to impact on both injury prevention and injury rehabilitation. Factors such as high stress levels can increase the risk of injury, whilst the occurrence of a
Heaney, Caroline
core  

Psychological Stress = PhysiologicalStress?

open access: yes, 2022
<jats:p> Abstract. The present study analyzed experimentally the association between the experience of psychological stress and the physiological stress response of prospective teachers. The experienced stress was assessed by self-reported data. Cortisol concentrations via saliva samples reflected the physiological response.
Ditzen, Beate   +3 more
openaire   +2 more sources

Ethical Precision in Nanoscale Brain Interfacing

open access: yesAdvanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Home - About - Disclaimer - Privacy